About Oral Peace For PET

“ORALPEACE for PET” is a pet oral care product jointly developed with pet lovers medical doctor, dentistry doctor, engineering doctor, agriculture doctor, veterinarian and dentist. This product adopts Japan’s advanced lactic acid bacteria research and biotechnology developed in collaboration with the National University of Japan, and adheres to the consistent concept of the ORALPEACE human oral care series that can be used safely at any age. It uses pure natural safe and swallow-able ingredients to provide oral and periodontal care for dogs and cats who are inconvenient to gargle.

“ORALPEACE” was co-developed together with Faculty of Agriculture – Kyushu University, Faculty of Dentistry – Kagoshima University, National Center for Geriatrics and Gerontology and Eco Friendly Institute for elderly, new-born babies and infants who are having difficulty to gargle, pregnant women and lactating mothers who do not want to ingest chemical ingredients. “Neonisin-e® *” the ingredient in ORALPEACE, is a revolutionary anti-bacterial agent extracted from antibacterial peptide (protein) and 100% plant extracts. This ingredient uses Japanese biotechnology to quickly respond to various pathogenic bacteria in the oral cavity.

“ORALPEACE” human range product launched since July 2013. In addition to medical institution and homes, it is suitable to use during shortage of water such as disasters and outdoor. The social initiatives of creating job opportunities for disabled people in Japan, ORALPEACE received various attentions, including the award of “Yokohama Business Awards” in 2014 and “JAPAN Venture Awards” in 2015.

In response to the demand of many cat and dog lovers, “ORALPEACE for PET” launched in February 2016. It has become a popular Japanese product not only in Japan, but also in the United States, Mexico, China, Hong Kong, Taiwan, Malaysia, Singapore, Europe, Australia and around the world.

In July 2017, our company held a presentation of “Neonisin-e” (Neonisin-evolution) research results in the Yokohama Port Opening Memorial Hall. “Neonisin-e” is a new formulation containing the essential oil of Bulgarian Damask Rose, is an evolutionary version of “Neonisin”. This patent achievement received high evaluations, including the first Japan Agricultural Chemistry Technology Award of this century for oral care products in March 2019.

The upgraded version of “ORALPEACE for PET” launched in January 2020. It uses the “Neonisin-e” ingredient to be more effectively respond to various oral pathogens. Along with the upgraded version, it has been better improved in terms of packaging, increased the volume per tube, changed the tube specification, and improve the viscosity.

“ORALPEACE for PET” series developed and shared the same concept as human ORALPEACE product, “Everyone can use, safe and easy oral care”. It is focusing on research and development, caring for the society, and wishing you are staying happily with your pets everyday.


  • People who want their pet to stay healthy
  • People who are worry about their pet’s body odour due to bad breath
  • Pet that is in hospital
  • Pregnant or nursing pet
  • Pet periodontal care before tartar is formed
  • People who care about food and what their pet can eat
  • People who hope that pet oral care can be done easily
  • People who value the brand background, concept and focus on product’s quality
  • People who like simple design even for pet products
  • People who want their pet to live safe, healthy and long-lived
  • People who worry about their pet’s oral problem
  • Senior pet
  • Pet daily oral cleaning
  • Tartar prevention and reduce unnecessary anesthesia
  • People who like products that has solid research background
  • People who do not want their pet to ingest synthetic ingredients such as chemical
  • People who like product from trusted stores
  • People who value the protection of the global environment
  • People who value social brands
  • People who value social brands
  • Pet that is taking medication and dry mouth
  • Puppy / Kitten
  • Pet daily oral care
  • People who pay attention to their family health
  • People who focus on product safety
  • synthetic raw materials, synthetic germicides, synthetic surfactant, synthetic preservatives, etc.
  • People who like eco-friendly products


By popular demand, we launched the “ORALPEACE for PET” series.

  • There are a few pet products that contain effective ingredients for solving oral problems, and very few of the products that are jointly developed by hospitals and universities using scientific methods.
  • The pets’ body are small, and hoped that the pet’s oral care products have undergone careful research and verification of effectiveness and safety.
  • Hope that effective oral care patent for human can also be applied to pet product.
  • It would be greatly appreciated if there are any pet care products that utilized research or technology that had an effect on the causative bacteria.
  • Hope that pet oral care products not only have good reputation, but also have the verification of effectiveness and safety.
  • Daily brushing is more difficult. An effective oral care product for pets would be more appreciated.
  • Hope there are high value-added oral care products that can help reduce total spending on the pet’s health, not just cheap low value-added products.
  • Products developed for humans being use for pets.
  • Hope that pet oral care products use food ingredients as safe raw materials, which will have a significant effect.
  • Hoped to use safe oral care products for pets to prevent disease entering from the mouth.
  • Hope oral care products are good for pets.
  • Hope to give pets family-like care and oral care.
  • Hope oral care products use 100% natural raw materials for puppies/ kittens to senior pets.
  • Hope that pet oral care products meet international organic certification standards and have high safety standard.
  • The trans-dermal absorption rate of chemical components through oral mucosa is 10 times more than the trans-cutaneous through skin. Pet’s parent doesn’t want to let the pets swallow the chemical components.
  • Hope pet oral care products will not put a burden on the global environment.
  • Under normal circumstances, general anesthesia is required for a pet to remove calculus, but there are always risks and concerns.
  • It is time consuming and the cost is high to remove calculus. Pet’s parent want to prevent it easily and effectively through daily brushing.
  • Bad breath will occur if pets’ oral is not taken care. They will easily have body odour after licking the fur. Eliminating bad breath will reduce the smell of pets, and it will be better to live with humans.
  • Hoped that pet oral care products will take into account the effectiveness and safety, and the price is reasonable.
  • Hope to get the pet oral care products with simple design.

Features of “ORALPEACE for PET”

  • Joint research and co-developed with Faculty of Agriculture – Kyushu University, Faculty of Dentistry – Kagoshima University, National Center for Geriatrics and Gerontology and Eco Friendly Institute. The research members including pet lovers medical doctor, dentistry doctor, engineering doctor, agriculture doctor, veterinarian, dentist and etc.
  • This product adopts biotechnology from Japan. It Contains lactobacillus bacteriocin patented formulation “Neonisin-e *”. The product’s research and innovation, technology patents, and convenience, sociality, and public welfare are recognized by public institutions only in Japan but worldwide. The ingredients used in this product have been verified by international institutions and various research institutions and are completely free of chemically synthesized ingredients. With 100% natural plant-derived ingredients and water as raw materials, there is no hidden safety hazard and it is safe to swallow for people and pets.
  • Both pet series and human series use the same ingredients, manufacturing methods, and factories that meet the standards of the international organic certification organization.
  • Rest assured that there are no chemically synthesized components and other components will absorb by the body through the oral mucosa.
  • Easy oral care is possible. Simply apply or dilute with water, no gargle needed.
  • Hypoallergenic and alcohol (ethanol) free. It can be used from puppies/ kittens to senior pets.
  • A refined design that enriches everyday life with the Good Design Award 2017. Reasonable price for long-term use.
  • ORALPEACE does not imitate or follow, and is determined to be an original brand.
  • ORALPEACE for PET supports facility dogs that providing comfort for children in hospital.
  • ORALPEACE business strives to provide employment opportunities for people with disabilities throughout Japan.
  • ORALPEACE oral care products bring warmth and happiness to you and your pets.

Key points of upgrading the “ORALPEACE for PET (gel)” released on 13 February 2020

  • Bulgarian Damascus Rose Oil was added to the original patented ingredient “Neonisin” and upgraded to “Neonisin-e”.
  • Thereby enhancing the sterilizing ability of oral candida, becoming a pet oral care product that more effectively responds to various pathogenic bacteria in the oral cavity.
  • Come with aluminum laminated tube and flip top cap, more convenient to use.
  • Improve the viscosity of the gel, better texture and taste milder and more natural Volume increased to 80g, price fixed same price.

* Cleaning aid

Product Line up

Contain “Neonisin-e® *” patented ingredients
ORALPEACE for PET Oralcare Gel (made with water and plant-derived ingredients)

Pamper your pet just like one of the family members with oral care products that can be used on a daily basis.
Apply a proper amount of the gel to toothbrush or fingertips, or apply the gel evenly to the mouth with clean fingers or gauze. After brushing or smearing, do not need to rinse with water. It can also be mix into pet’s drinking water for simple care. It is completely free of chemical synthetic ingredients, synthetic preservatives and synthetic germicides. Except for water, all ingredients are derived from plants, the taste is mild and refreshing, and the paste is colorless and transparent.


  • Content:80 g(about 2 months usage)


See package for all ingredients.

Contain “Neonisin®” patented ingredients
ORALPEACE for PET Refresh and Cleansing Liquid (made with water and plant-derived ingredients)

Pamper your pet just like one of the family members with oral care products that can be used on a daily basis.
Contain “Neonisin®* ingredients, keep your pet’s mouth clean, prevent bad breath, and stay healthy. ORALPEACE for PET is simpler and safer. Spray it directly into the mouth several times, or open the pet’s lips and spray it on the upper and lower teeth, brush or smear the teeth with clean fingers or gauze. Do not need to rinse after use. It can also be sprayed in drinking water for simple care.It is completely free of chemical synthetic ingredients, synthetic preservatives and synthetic germicides. Except for water, all ingredients are derived from plants, the taste is mild and refreshing, and the paste is colorless and transparent liquid.

ORALPEACE for PET Refresh and Cleansing Liquid

  • Content:30 ml(about 2 months usage)


See package for all ingredients.

* The product upgraded in February 2020 is only for gel product

Designed by Noriteru Minezaki ((Studio))

The following ingredients are not used

ORALPEACE do not contain the following ingredients:
x Chemically synthesized ingredients
x Alcohol (ethanol)
x Synthetic fungicides such as cetylpyridinium chloride / benzethonium chloride / chlorhexidine gluconate / IPMP (isopropylmethylphenol), and triclosan
x Synthetic surfactants such as sodium lauryl sulfate
x Synthetic preservatives such as paraben, phenoxyethanol, sodium benzoate, sorbic acid K, propylene glycol and BG, etc.
x Synthetic fragrance
x Abrasives such as calcium carbonate, silica, microbeads and zeolite
x Nanoparticles
x Synthetic colorant such as Cyan No.1
x Soap base (foaming agent)
x saccharin
x Petroleum-derived components
x Honey Propolis
x Raw materials of animal and human origin
x Genetically modified raw material

* Cleaning aid

How to use

for PET (gel)

Use toothbrush or finger cot

Apply a proper amount of the gel to toothbrush/ finger cot or apply the gel evenly to the mouth with clean fingers or gauze. After brushing or smearing, do not need to rinse with water. Can also be used with molar toys.

Dissolved in drinking water

You can dissolve the gel in drinking water, stir it with clean fingers, and use it.

for PET (spray)

Spray directly in the mouth

Simple care when going out, sleeping, and spraying in drinking water.
Spray it directly into the mouth several times, or open the pet’s lips and spray it on the upper and lower teeth, brush or smear the teeth with clean fingers or gauze. Do not need to rinse after use.

Dissolved in drinking water

It can also be sprayed 1-2 times in drinking water for simple care.

Supported by Certified NPO corporation Shine On Kids アイビー(Labrador Retriever female)


Other videos and articles can be viewed on the Web.

Q  &  A

First is the confirmation of “all components”.

When you buy a product to put in your “mouth”, which is the entrance to all of your important physical and health needs to create the body and mind of your beloved family, be sure to buy “all ingredients” of each product ( It is recommended that you check and check (ingredients of) by yourself before selecting.

“All ingredients” can be found on the product packaging.

Often, it’s easy to get distracted by “other than the essence of the product.”

However, in the world of science, research, and manufacturing, all new research and technological innovation and safety-related efforts and efforts that underlie the products result in the achievement of “all ingredients.”

It is important to check “all ingredients” and determine the essence of the product.

Second is the confirmation of “research background” and “results”.

What kind of project members, universities/graduate schools and research institutes (whether national or private, internationally competitive public institutions),

What kind of career and profile the researcher has (researcher who can have international competitiveness in his/her institution or field of expertise) has researched and developed the technology/product, and what they are doing. Or

And whether there is innovation or objective superiority (“patent”, “thesis”, “award history”, “newspaper publication”, etc.) in the research/technology,

It is an era where you can easily search “research background”, “data”, “papers”, “patents”, “awards” and “media publications” for each product on the Internet.

It is important to identify what kind of research institute, researchers, involved members, etc. are engaged in the “research background” and what “results” are obtained as a result.

Thirdly, what kind of newspapers, televisions, and other news media, and public media, such as magazines, handle these research results and products?

Is it a research result or product that has value as news that is treated as an article rather than an advertisement by a reliable news agency or public media?

Received press releases from many research institutes and companies every day, and made into articles and reported through filters of exhausted reporters are research results with new social usefulness for many consumers without expertise. It will be a big factor to judge whether or not it is a product with unprecedented value.

Fourthly, what kind of medical institution/store is selected and in what countries are they sold and used?

For highly reliable medical institutions and stores such as department stores, it is the responsibility of medical personnel who select various products in the world at their own risk and provide patients and customers with products that their hospitals and stores can proceed with confidence. There are buyers (purchasing staff).

With so many things and information overflowing around the world, there are shops with high-class stores that consumers can buy without doubt.

It is said that being selected by those medical institutions and department stores is a product that is selected by a filter of discerning buyers who are overlooking products all over the world, trusted, and recommended to important patients and customers. It will be a thing.

Also, in order to be officially sold locally not only in Japan but also in overseas countries, it can be sold only after strict approval by the health organizations in each country.

The products that are officially sold locally are those that have been carefully examined in their respective countries and judged to be used as those that contribute to the health of the people.

What kind of medical institution, government agency, public institution, and what kind of store and department store should you choose?

Is it a product that is sold not only in Japan but also in the US, Europe, China, Asian countries, Latin America and other countries around the world? And is it a product that is needed by many people around the world?

It is also important for many consumers who do not have specialized knowledge to know the handling and sales results of the product calmly because of the difference from other products in the world, the essence of the product, the superiority of research and technology, and the product to be selected. It is a factor to judge the goodness.

Finally, it is confirmation of “sociality”.

Whether the product/business depends on the selection and is good not only for yourself but also for society and other people, whether it is a product that gives priority to human health and environmental consideration, is a product for mere commercial purposes, or is social It is important to check if the product you are working on.

We are now in an era where the actual conditions and management attitudes of the above companies can be easily checked on Wikipedia.

It is important for medical professionals and consumers to judge smartly not only the product specifications themselves, but also the “sociality” of products and companies.

With a wealth of information, companies and products, it is important to be able to identify and judge the essence in order to protect the health of ourselves, families and patients, and to protect our health and lives. The time has come for us.

In the era after the coronary virus crisis, which has changed drastically from the past, each medical person and consumer knows how corporate products will lead to better things for society and themselves, We need to change to a wise choice.

Humans and pets, who are animals, have the same functions and structure of the oral cavity such as teeth, gums, and saliva.

In the case of dogs, the PH in the oral cavity is different than in humans, and the types of bacteria that are resident in the oral cavity are slightly different, but there is not much difference in oral function.

There is also no significant difference between toothpaste and oral care products for humans and pets.

If you want to check the efficacy and safety of your beloved pet’s oral care product, it may be one way for the owner to try it for himself.

Whether you want to use it for yourself, including safety, how you feel by brushing your teeth yourself, whether you think it is okay to swallow it like a pet who can not gargle or spit, actually use it Can you feel the effect for yourself?

ORALPEACE is developed for humans who cannot gargle or spit, such as infants, pregnant women, the elderly and fighters, and has the same ingredients as human products (prescription that eliminates unnecessary taste in pets) and is safe under the Pharmaceutical Affairs Law. Made in a domestic certified organic factory under a high production system.

A product that responds to the needs of pet dogs and cats who want to use products that have the same level of safety and efficacy as the ones for humans that are loved and loved by humans and that have been researched and developed by Kyushu University. We are working on manufacturing.

ORALPEACE Forpet is a human-grade product that is made of the same materials as those for humans and infants, and manufactured under a strict hygiene and production control system at an organic certified factory, and can be used by humans and infants.

Before you use it on your favorite pet, please try the product that you put in the mouth of an important pet by yourself, it seems that you may swallow it by yourself, the quality of the product such as taste, ingredients, hygiene and production control We recommend that you use it as an important pet’s mouth after experiencing, trying out and comparing the effects and research background.

“Oral care products, oral hygiene agents, oral moisturizers and oral moisturizers for pets and dogs that are expected to have the function of preventing tartar and bad breath while simultaneously brushing, periodontal and oral care for pets and dogs”・The following are the selection points for oral care products.

First and foremost, try the tasting yourself. With this, you can understand most of the differences, such as “feeling whether it is a safe ingredient even if swallowed as it is” “feeling whether it feels good or bad when put in the mouth” “real feeling of effect of using” I will.

Secondly, it may be important to confirm whether or not “ingredients that are expected to have safe antibacterial properties even if swallowed” are included.

In order to prevent the increase of bacteria causing troubles in the oral cavity, simple gel cannot meet the needs of clinical sites, and “a product containing an antibacterial agent that is safe to swallow” should be kept clean, moisturized, and clean in the oral cavity. Is considered to be highly useful.

The third major point is the usability of pets and dogs.

Materials that contain a large amount of chemical components such as synthetic thickeners and synthetic polymers, which are not food products, have low raw material costs, but have problems in terms of usability and water solubility. In other words, it feels like a foreign body in your mouth and you feel uncomfortable. For example, it feels like vaseline, lard and paint cling to your mouth all the time.

You can also check the water solubility of each product at home.

Put a small amount of the product you want to compare with a petri dish (a small plate is also acceptable).

Then add water and leave for about 1 hour.

Finally, drain the water and watch the condition of the remaining product.

If it remains unmelted, it will feel like sticking to the upper jaw. There is a type that remains almost as it is even if it has water (saliva), to a type that spreads naturally and thinly, like “Oral Peace Fourpets”.

Substances that are difficult to dissolve that contain a large amount of chemical raw materials are difficult to digest in the body and decompose by microorganisms in the intestinal tract, and are difficult to decompose even if they are discharged to the natural world, making them difficult to biodegrade by microorganisms.

Does it not dissolve in saliva and feel good as it stays in the mouth, or is it comfortable to spread in the mouth and feels comfortable to work with? We recommend that you choose the best product.

It is important to thoroughly understand the research and development background of each product and the characteristics such as feeling of use, and select the product that suits the needs of the pet or dog to be used.

It is a coined word that combines oral and peace.

It is said that about 700 kinds of bacteria are always present in the oral cavity, and they maintain a balanced and healthy condition.

If this calm balance is disturbed and the total number of bacteria increases too much, you will end up in an unhealthy state and get sick.

Therefore, we named it “ORALPEACE” in the sense that “it maintains a peaceful state in the oral cavity with safe ingredients.”

It also expresses peace of mind, family health and peace.

It is made in Japan.
Animals, just like humans, they will have tartar due to oral bacteria, which form calculus after hardening.

Oral bacteria can also cause bad breath and periodontal disease. By reducing oral pathogens through daily oral care, they can prevent tartar, calculus and bad breath.

On the other hand, animals are not able to gargle need ingredients that are safe and effective when swallowed. Using synthetic fungicides to animals always a topic for clinical challenges.

Hence, research and development of a new formulation that effective against causative bacteria and being safe even if swallowed has been desired by pet dogs and cat lovers around the world.

Synthetic fungicides made from petroleum and chemical ingredients have excellent bactericidal activity, but there is a risk of their effects on the body.

“Neonisin-e” derived from plant ingredients is gentle on animals and has no side effects.

Although lactic acid bacteria can produce antibacterial substances themselves to exert antibacterial properties, it is difficult for live lactic acid bacteria to stay in the oral cavity.

The time required for the production of antimicrobial substances and the amount of output are also unstable. It is difficult to achieve the desired effect.

In addition, there are approximately 100 species of antimicrobial peptides derived from lactic acid bacteria have been discovered in the world, including human and animal sources. Only “Nisin A” is approved in Japan, others are unapproved substances.

Neonisin-e® *” is a natural antibacterial agent with high antibacterial activity, which is highly refined with a unique method and then combined with plant components.

Its action structure is that it adheres to the cognitive site (lipid II) of the cell membrane of the target bacteria, and perforates the bacteria instantly.

The most important features are stable effect, quick action and safety. (Patent No. 5750552)

For more information, please refer to Neonisin’s website.

In Japan, it is a legal obligation to conduct experiments on animals such as rabbits, mice and other living organisms for ingredients such as synthetic fungicides.

ORALPEACE products do not require animal experiments because we do not contain the above ingredients.

We develop and manufacture products with the aim of not sacrificing small animals.

The pet series and human series of ORALPEACE products are completely the same from ingredients to production process. Pet series products can also be used by human.

However, we recommend that humans and pets use oral care products separately to avoid cross-infection of oral bacteria between humans and pets.

Although ORALPEACE for humans can also be used for pets from the ingredients, we do not suggest you to do so because human series has a stronger taste. Therefore, it is recommended to use a mild-tasting pet series for your pets.

ORALPEACE products are safe to swallow, so eating one tube of gel has no effect on the body.

However, it is recommended to keep the product out of the reach of pets.

You can use it as many times as you like.
ORALPEACE products have sold hundreds of thousands since it’s released, and no cases of allergies and side effects have been received.

If your pet is allergic to a certain substance, please confirm the ingredients of the product and check with the doctor to determine whether to continue use it or not to.

ORALPEACE has the same ingredient as food, so you don’t have to worry about it.
There is no problem if it is kept in good hygiene.
No strict ratio is required. Take a small amount of gel with your clean fingers and dissolve it in water,: for spray, spray 1-2 pushes. In order to keep your pet’s drinking water clean and fresh, please change the water once a day.

If your dog has calculus, just applying gel and drinking water cannot completely prevent calculus. Brushing is needed.

Please refer to the purchase method page.

If you can’t find a store near you, we would appreciate it if you ask a nearby retailer, pet shop, pet salon, veterinary hospital, etc. to order ORALPEACE.

Regarding the safety of essential oils for cats, in 1990s in US, cats became sick after applying a product containing high-concentration distilled tea tree essential oil directly on the skin of cats. Since then, it has been verified that the ratio of tea tree essential oil for cat products must be less than 1%.

However, there is no credible scientific research show that essential oils are harmful to cats.

Some people think that cats have no metabolic capacity for essential oils and avoid using products containing essential oils. Some people think that high-concentration tea tree essential oils are safe for cats, and some essential oils are dangerous for cats. None of the above opinions have been confirmed by relevant experiments and research, and the actual situation is unknown.

In addition, pet products (categorized as daily necessities) do not require all ingredients to be listed like cosmetics and pharmaceutical products. Many products simply described as “preservatives”, but actually contain chemically synthesized ingredients or preservatives. (ORALPEACE products list the full ingredients).

The amount of ingredients usually varies depending on body size. Smaller cats might have greater impact as compare to larger animals.

ORALPEACE is made of pure natural plant-derived ingredients. There is only very small amount of mint essential oil (below 0.1%) for the purpose of preservation. According to the method of use, if the product is diluted with pet saliva or water, the intake of essential oils is very small, and it will not adversely affect the pet.

Safety always the first concern in ORALPEACE development process. However, every cat are different. If you have any safety or allergy concerns after use, please suspend and consult a doctor.

Is fragrant oil harmful to dogs and cats? (Source: Homepage of the Japanese Veterinary Society)

The major differences are:

“It contains the patented formulation “Neonisin-e®”.”

“We are conducting research to respond to bacteria that cause oral problems with safe ingredients.”

Safe to swallow, 100% naturally derived, only food ingredients, organically certified toothpaste, oral care products can be made without the need for basic research or patented technology at national universities or research institutes.

Regarding ORALPEACE, we think that it is almost the same as other safety-promoting oral care products unless “Neonisin-e®︎” is added.

Gels with similar shapes can be easily and inexpensively made at home if you purchase the materials at online shops.

[How to make a toothpaste gel]

In the case of “Toothpaste Gel”, refer to the ingredients of your favorite product and refer to the ingredients of glycerin (moisturizer) and mint essential oil or orange essential oil (preferably organic certified) and thickener xanthan gum at online shops etc. If you purchase it and mix it at home, you can make a toothpaste gel with 100% food ingredients that are safe ingredients made only from food ingredients.

If you want sweetness for children, xylitol, which is an alternative sweetener for sugar, is also sold at online shops, so you can mix it.

Also, if you want to see if lactic acid bacteria (itself) actually has an effect or effect on the oral cavity and teeth, mix the yogurt supernatant (lactic acid bacteria fermentation extract/whey) or yogurt itself (live lactic acid bacteria) I think that is also good.

If the lactic acid bacteria contained in the product are alive, it is possible to make it by culturing and fermenting the bacteria from milk at the home in a yogurt maker.
(Products such as yogurt that are sold in refrigerated storage without preservatives and bactericides. Products that are distributed at room temperature will ferment and decay when lactic acid bacteria are alive. It is inactive because it is sterilized by mixing with a strong alkali, and the lactic acid bacteria have been killed and left behind.)

[How to make natural toothpaste (abrasive)]

In the case of “natural toothpaste”, similarly, calcium carbonate, Ca carbonate (abrasive, limestone powder, white line powder on the playground, raw material for chalk), glycerin (moisturizer), and mint essential oil (with organic certification) Is preferred), and you can easily make natural toothpaste powder by purchasing it at an online shop or drug store and mixing it with water at home.

In addition, you can get your favorite plant extract, essential oil, xylitol, propolis, sodium hydrogen carbonate (baking soda, polishing action, strong alkali), salt (polishing action, preservative), other polishing agents, etc. at the online shop. It is an ingredient that is easy to obtain, so I think you can try mixing it.

You can purchase undiluted solutions of almost all of the above materials and various ingredients and extracts that have been appealed as key ingredients of cosmetics at online shops.

I think that it is a good opportunity to actually try on your own oral cavity and teeth and judge for yourself what kind of effect these ingredients can be expected and realized clinically in the oral cavity and teeth. ..

The above is not a patentable ingredient, so anyone can mix it to make a toothpaste gel or paste.

However, in order to respond to the needs of the new 21st century and to cope with bacteria causing troubles in the oral cavity in clinical settings of medical care and nursing care, a patent for lactic acid bacteria antibacterial peptide invented in joint research with Kyushu University etc. over 10 years The formulation “Neonisin-e®” (cleaning aid) is a research result/invention that plays a major clinical role that could not be realized with conventional ingredients of natural origin.

To experience the difference, use an interdental brush or floss to clean the spaces between your teeth with the oral piece in your mouth before bedtime, and use a tongue brush (a toothbrush may be used) to clean your tongue. After cleaning and rinsing again, we recommend that you spread a small amount over the entire mouth, teeth, interdental space, periodontium, and tongue.

The next day after carefully taking care of your mouth and resting, you will be able to experience the changes in bad breath and mouth refreshment when you wake up.

We believe that ORALPEACE has no new significance for humankind as a product unless it contains “Neonisin-e®”.

The major differences are as follows.

Regarding research on response to bacteria causing oral problems,

“Use of lactic acid bacterium antibacterial peptide “Neonisin-e®︎” instead of conventional synthetic bactericides and alcohols”

“The product is made only from food ingredients that are considered safe even if swallowed.”

“Chemical synthetic ingredients such as synthetic bactericides and alcohol are not added to the product”

We are responding to the new world-wide medical and nursing care clinical needs and consumer needs, bacteria that cause oral problems.

“I want to use ingredients that are safe to swallow,”

“I would like to use a safe antibacterial agent that replaces conventional synthetic antibacterial agents, alcohol (ethanol), and highly concentrated plant antibacterial agents with side effects.”

In order to respond to the aging of the world and the paradigm shift towards the consumer’s safety and health consciousness, a century after the birth of toothpaste, the lactic acid bacterium antibacterial peptide “Neonisin- e®” research.

ORALPEACE is a new product invented and developed in Japan in the 21st century for the following people.

Worried about problems in the oral cavity,
I’m careful about what I eat,
We are committed to family health and prevention,
Want to avoid daily oral intake of chemical ingredients,
Pregnant woman/lactating
I don’t like additives or synthetic fungicides,
Elderly people and illnesses requiring nursing care who have difficulty gargle or spit and accidentally swallow the product,
And I do not want to destroy the natural environment with persistent chemical products.

And ORALPEACE is a product for people all over the world who really need ORALPEACE not only to pursue the superiority of the product but also to sympathize with the background of the brand and contribute to society through the business.

ORALPEACE has been developed with the aim of making it a product that can be used by infants, the elderly who need care, elderly people who are difficult to gargle and vomiting, fighting persons and people with disabilities.

Originally, we have spent a lot of time researching and developing foods that human beings have eaten since ancient times, and products that use only plant-derived food ingredients whose safety has been verified by insurance organizations around the world.

Therefore, we do not use chemically synthesized ingredients, petroleum-derived ingredients, or even plants that have no edible history.

Even if it is recognized as a raw material for food, it was developed with the policy of not adding chemical synthetic components or petroleum-derived components.

Regarding the antibacterial peptide (bacteriocin) that may be produced by the compounded lactic acid bacteria component, those that have not been approved as food or food additives after undergoing safety verification by the World Health Organization or the Japanese Ministry of Health, Labor and Welfare Is not used at all.

There are various kinds of “lactic acid bacteria” that you can eat.

Lactic acid bacteria taken from plaque in the mouth of people who cannot brush their teeth but have caries or periodontal disease, and lactic acid bacteria ingested from other people’s mouth or excrement are unapproved substances as food. ..

The only ingredients used in ORALPEACE are those approved by WHO, GRAS certified in the United States, and approved by Japan’s Ministry of Health, Labor and Welfare as foods.

Regarding antibacterial peptides (bacteriocin), we also avoid blending non-approved food products.

Not used

ORALPEACE is made from water and all-edible plant-derived food ingredients.

ORALPEACE is a product newly developed for elderly people requiring nursing care, fighting patients, infants, etc. who have difficulty in gargle and vomiting. It was created with a lot of effort and more than 10 years.

All ingredients, except water, are made from plant-derived food ingredients. It is made entirely of plant materials that are sustainable and environmentally friendly, rather than limited fossil materials such as petroleum.

Synthetic agents derived from petroleum such as cetylpyridinium chloride (also known as cetylpyridinium chloride/CPC), benzethonium chloride, chlorhexidine gluconate, IPMP (isopropylmethylphenol), and triclosan, which are chemically synthesized from light oil, etc., are not added.

The above are extremely powerful bactericides, and the Ministry of Health, Labor and Welfare strictly limits the compounding percentage in products, and there are side effects to the action.

However, in practice, among the petroleum-based synthetic bactericides, it has been recognized in the world’s research that a concentration of 0.1% or more is effective, but in one country, the concentration recognized in product formulations is 0.05% or less. As a product, it is difficult to expect actual clinical effects.

On the other hand, side effects such as taste disorders and black hair tongue may occur due to long-term use even at low concentrations where no effect can be expected, and there have been difficult problems with actual clinical use.

For details on the synthetic fungicides derived from petroleum, their effects, side effects, and their environmental impact, please do your own research on the Internet.

Not compounded.

Alcohol (ethanol) is not added so that it can be used by infants, those who do not want to take alcohol, and those who are dry.

Alcohol has the effect of clearing the inside of the mouth and not spoiling the product, but it may cause damage to the oral mucous membranes, thirst in the mouth, and dry teeth in the oral cavity. There are side effects that can cause trouble.

Therefore, it is unblended in ORALPEACE.

If you like alcohol (ethanol), we would appreciate it if you could get a high-frequency alcohol product from a pharmacy or a liquor store and use it with ORALPEACE.

Do you mix bleaching agents such as chlorine, chlorine dioxide (CIO2), sodium chlorite, sodium hypochlorite, chlorine-based gas, etc.?

ORALPEACE does not contain bleach, chlorine, chlorine dioxide (CIO2), which is a deleterious substance used for disinfecting and disinfecting pools, sodium chlorite, sodium hypochlorite, chlorine-based gas, etc. ..

ORALPEACE has devoted a great deal of time to research and development aiming at products that can be used by elderly people, fighters and people with disabilities who require nursing care, which makes it difficult to gargle and spit.

Please investigate the effects, side effects, and effects on the human body of chlorine and chlorinated gases on the Internet by yourself.

All components of ORALPEACE are made from plants (food) except water.

It is made entirely of plant materials that are sustainable and environmentally friendly, rather than limited fossil materials such as petroleum.

Also, ORAL PEACE is a product that you can put into your mouth.

Regarding the lactic acid bacteria used during the production of “Neonisin-e®”,

Not “animal-derived fungus” that lives in “excretion” in the intestinal tract of “animal”, which is found from human or animal feces, etc.

We use “Lactococcus lactis”, which is a “plant” found in “Tofu” from Japan and a “plant-derived fungus” that lives in “food”.

Not compounded.

ORALPEACE contains the bacteriocin preparation “Neonisin-e®︎” (cleaning aid), which is a highly purified lactic acid bacterium peptide produced by lactic acid bacteria.

Regarding the clinical effects of adding “lactic acid bacteria” itself to oral care products, we would like to ask you to visit the website of “Neonisin” for the past problems by research institutions around the world.

In addition, there is a big problem that “a product containing lactic acid bacteria” and the following ingredients “cannot be combined together”.

“Antibacterial substances” and “preservatives” “alcohol (ethanol)” “synthetic germicide” “sodium hydrogen carbonate (baking soda/alkali)” etc.

Because, “antibacterial substances” such as lactic acid bacterium bacteriocin, “preservatives” such as paraben, phenoxyethanol, sodium benzoate, K sorbate, alcohol (ethanol), “synthetic germicides” and “sodium hydrogen carbonate (sodium bicarbonate/alkali)” )” is for killing the “lactic acid bacteria” mixed together.

Also, if you want to use oral care products that can be stored and used at room temperature instead of refrigerated storage like yogurt, it is necessary to sterilize because “lactic acid bacteria” will perish if they are alive.

Therefore, a product that contains both “lactic acid bacteria” and “antibacterial substances” is said to have “combined both components that evoke the effect.”
Actually, “lactic acid bacteria” have been killed by “antibacterial substances” etc., and there was a problem that it became meaningless in use and clinical.

ORALPEACE contains “Neonisin-e®︎”, which is a purified peptide produced by lactic acid bacteria, and does not contain “lactic acid bacteria” itself.

ORALPEACE does not contain lactic acid bacteria itself, but “Neonisin-e®︎” is produced from lactic acid bacteria.

The lactic acid bacteria used for the production are explained below.

Even if you say “lactic acid bacteria” that you can eat, their habitat and origin are various.

Even if you say “lactic acid bacteria” with a good image, it will be completely different depending on the bacterial species and strain.

There are also lactic acid bacteria derived from the ground, rivers, insects and animals, and humans. There are also lactic acid bacteria that live in the intestinal tract (feces) and excrement of animals, and in blister and sludge.

There are also lactic acid bacteria found in plaque accumulated in the mouth of people who cannot brush their teeth but have caries or periodontal disease, and lactic acid bacteria found in the feces and dirt of other people.

In fact, the strains of adult feces and dental plaque are often stronger than the bacteria of infants and children’s feces and dental plaque, and the product contains bacteria isolated from adult human feces and dental plaque. The reality is that they are often used.

However, until now, in the practical application of lactic acid bacteria research by research institutes all over the world, yogurt, beverages and oral products produced by fermenting feces and plaque of other people have been consumer-oriented and are themselves, families, children and patients. There was a big problem that I didn’t want to put it in your mouth.

Regarding the antibacterial peptide (bacteriocin) that may be mixed in the “fermented products” of the bacteria derived from feces and dental plaque, there is a possibility that the habitat of the bacteria may be effective against miscellaneous bacteria. Antibacterial peptides (bacteriocin) other than “A” are unapproved substances that have not been verified for safety by WHO, the world health organizations, or the Japanese Ministry of Health, Labor and Welfare.

The lactic acid bacterium “Lactococcus lactis” contained in ORALPEACE is a lactic acid bacterium discovered in “Tofu”, a clean and safe food produced in Japan.

And for decades, a lactic acid bacterium that lives in plant-derived foods that mass-produces lactobacillus antibacterial peptide “Nisin A”, which has been licensed all over the world. It is a research result.

The lactic acid bacteria used in ORALPEACE are clean and safe lactic acid bacteria found in foods derived from edible plants called tofu, so you can safely put them in your mouth.

For the type and origin of lactic acid bacteria that you put in your mouth, we recommend that you check the name of each bacterium on the Internet.

Not used at all.

As mentioned above, this point is a major advantage of ORALPEACE in the world due to the background of long and deep research including the world’s leading researchers in lactic acid bacteriocin research.

ORALPEACE is a product that you can put in your mouth.

Not “animal-derived fungus” that lives in “excretion” in the intestinal tract of “animal”, which is found in the feces of humans and livestock

Regarding the lactic acid bacteria used during the production of “Neonisin-e®”,

We use “Lactococcus lactis” which is a “plant” found in Japanese “tofu” and a “plant-derived fungus” that lives in “food”.

For the type and origin of lactic acid bacteria that you put in your mouth, we recommend that you check the name of each bacterium on the Internet.

The labeling of “Neonisin-e®︎” is “Lactic acid bacteria culture extract”, “Plum fruit extract”, and “Damask rose oil”.

This is because “Neonisin-e®︎” is a mixture of the above ingredients.

Ordinary “lactic acid bacterium culture/fermented extract” is a liquid obtained by fermenting lactic acid bacteria, and in many cases, it is like the supernatant of yogurt. And many things such as water, impurities, and salt are turbid in the fermented liquid.

On the other hand, “Lactobacillus culture extract” used in “Neonisin-e®” is very different from other fermentation broths, and only the antibacterial peptide “Nisin A” produced by lactic acid bacterium from the fermentation broth fermented It will be isolated and highly purified by biotechnology.

It is “highly purified nisin A” as a highly pure lactic acid bacterium antimicrobial peptide liquid that can be extracted from a normal lactic acid bacterium fermentation liquor in an amount of only about 1/10, manufacturing costs and labor are more than 10 times.

Highly purified “Nisin A” has a 100 times or more difference in purity, degree of purification, stability and effect from the fermentation liquid of normal lactic acid bacteria.

The patented ingredient “Neonisin-e®︎”, which has been researched and developed through industry-academia collaboration with Kyushu University, etc., has the same label name as other “lactic acid bacterium culture/fermentation extract” “enzyme” etc. However, the reality is that the dimensions are completely different.

Not compounded.

Sodium hydrogen carbonate (baking soda) is an alkaline substance that has the effect of floating dirt and destroying and decomposing fats and oils and proteins.

In addition, the particles are large and difficult to dissolve in water, which makes them useful as an abrasive for kitchens.

Toothpaste containing sodium hydrogen carbonate (baking soda, polishing agent, alkali) was born about 100 years ago and can be easily made with baking soda in the kitchen.

However, there are various problems that are not recommended for use in tooth brushing and oral care in the modern oral clinics around the world.

First of all, the point that “the teeth are scraped by the polishing action”.

Sodium hydrogencarbonate (baking soda, abrasives, alkalis) is a substance that has a very strong polishing action, as it is also included in cleansers that remove stubborn dirt.

The American Dental Association (ADA) does not recommend sodium bicarbonate (baking soda) for the following reasons:

Particles of sodium hydrogen carbonate (baking soda) are said to be coarser and larger than any of the abrasive components of commercially available dentifrices, which is the same as brushing teeth with a file or cleanser.

After daily polishing, the enamel is scraped off every day, and symptoms of hypersensitivity will eventually occur, prone to tooth decay, pigments will easily remain on the scratches on the tooth surface and cause yellowing, and eventually dentin inside Is visible, and the teeth are gray, over white.

And the tooth that has been scraped will not return to the original, so be careful.

Next, it is “inducing excessive intake of salt”.

Sodium hydrogen carbonate (baking soda, abrasives, alkalis) is composed of sodium compounds as well as salts.

The amount of sodium hydrogen carbonate (baking soda, abrasives, alkalis) that can be taken daily by healthy people is less than 5 grams.

If you accidentally swallow it with toothpaste or gargling with sodium hydrogen carbonate (baking soda, abrasives, alkalis), you will ingest too much salt. Also, salt will be absorbed from the mucous membranes of the oral cavity without swallowing.

In particular, caution is required for those with impaired kidney/cardiopulmonary function, those with salt or sodium restriction, those with high blood pressure, and those with restricted salt intake due to chronic illness.

Also, it is not good for healthy people to increase their salt intake. Excessive salt intake leads to symptoms of metabolic disorders such as swelling and alkalosis.

Secondly, “alkaline tilt in the mouth causes tartar to adhere”.

The human body’s oral cavity has the physiological function of keeping the same weak acidity as the skin, keeping the PH in the mouth constant, suppressing the action of causative bacteria, and promoting the remineralization action of teeth.

Humans’ mouth is kept weakly acidic by saliva, but tartar is more likely to adhere to the mouth which is inclined to alkali.

Tartar is a plaque that is a collection of bacteria that is calcified by alkali and causes dental caries and periodontal disease.

There is also the expectation that “the neutralization of the mouth, which is inclined to be acidic by diet, may promote remineralization of teeth and prevent tooth decay”, but in reality remineralization is performed by saliva minerals.

Caries do not occur because the inside of the mouth becomes acidic, but the teeth are melted by the acid produced by the dental caries that live in the mouth to decompose sugar.

Ordinary weak acidity in the oral cavity does not activate dental caries (it cannot be inactivated even by tilting it to alkaline), so there is no point in temporarily tilting the oral cavity to alkali. There was a clinical problem that the bacteria could not be eliminated (oral mucosa and skin tissues were damaged before that), but the risk of tartar was increased.

Finally, the point is that “strong stimulation with alkali damages the oral mucosa.”

When treated with a strong alkali, it becomes the same as reduced bleach and strong alkaline ionized water, and strong alkali can sterilize general bacteria and inactivate viruses.

Strong alkalis are as good as disinfectants for medical equipment and kitchens, just like disinfectants such as chlorine and hypochlorous acid. However, there is a problem that it causes damage when used on the body of people who are composed of various bacteria.

Although strong alkali sterilizes bacteria, chemical damage destroys the proteins that make up the oral mucosa, damages the gum tissue and periodontal skin tissue, and damages the oral mucosa, deteriorating the oral condition.

When making skeletal specimens of animals because of their characteristics of destroying skin tissues and proteins, they are boiled with sodium hydrogen carbonate (baking soda).

Also, if you add baking soda to oil-dirty kitchen utensils, clogged ceramic filters, and parts of cars and motorcycles, the oil and protein will be decomposed and it will be very clean. Please try.

And regarding the effect data on bacteria and viruses, in experiments such as petri dishes, we can get data that reducing bleach and strong alkaline ion electrolyzed water can kill various bacteria and viruses.

However, in the actual oral clinic, the concentration cannot be maintained by being diluted with saliva (the skin damage is large if it is not diluted with saliva), and the reality is that the same clinical effect as the experimental data on petri dishes cannot be expected.

From the above, there was an oral clinical problem that strong alkali had more side effects than action and could not be used for babies and infants with weak oral mucosa, elderly people, fighters, and people who care about salt and are healthy.

Therefore, ORAL PEACE is a prescription that does not contain it.

However, if you like sodium bicarbonate (baking soda, abrasives, alkalis), baking soda for food is sold at supermarkets, so please use it with caution.

ORALPEACE is made from only food ingredients that are safe to eat, and we do not mix non-food abrasives (compounds, stone powder, etc.).

Abrasives (compounds, stone powder, etc.) can be whitened by scraping the tooth surface, but they have the following side effects.

Enamel does not return to the original state if it is cut too much.

It becomes hypersensitive due to excessive shaving.

Accumulates on the periodontium.

We do not have the following abrasives in ORALPEACE.

Calcium carbonate (raw powder for drawing white lines on playground, raw material for chalk)
Sodium hydrogen carbonate (baking soda)
Mud (clay and montmorillonite)
Micro beads (plastic powder)

ORALPEACE can be used safely with only edible ingredients, and it is also suitable for whitening teeth by carefully brushing teeth for a certain period of time without damaging enamel and dentin, and for use with electric toothbrushes.

ORALPEACE can also be applied to the oral cavity as a moisturizing gel for the oral cavity.

Regarding “keeping teeth white”, our research team recommends the following methods.

Instead of shaving away the enamel and dentin of your important teeth with an “abrasive” to make your teeth look white (which was the standard in the past), perform daily home maintenance by careful brushing.

To have a whitening treatment in a clinic once a year or once every few months.

We believe that it is a reasonable way to keep your beautiful white teeth, both effective and safe, just like removing stains on your skin.

Synthetic preservatives such as methylparaben, butylparaben, propylparaben, also known as paraoxybenzoate, are not added at all.

In addition, we do not use other synthetic preservatives that are used in place of parabens in our oral pieces.

All ingredients of ORALPEACE are as shown on the package.

Please check the effects, side effects, and environmental effects of synthetic preservatives on the Internet yourself.

Not using

Phenoxyethanol is a synthetic preservative/preservative that is increasingly being used as a substitute for consumers who do not like parabens.

It is chemically synthesized in the presence of an alkali metal hydroxide or alkali metal borohydride by hydroxyethylation of phenol (a colorless needle-shaped crystal made from coal tar, which is used for preserving and disinfecting).

In Japan and the European Union, the amount of phenoxyethanol is strictly limited for cosmetics for skin, and up to 1% can be added to the product.

However, it is a banned ingredient for use in food.

(Paraben is allowed to be used in food.)

Even for cosmetics for the skin, the inclusion of phenoxyethanol is prohibited by international organic product certification standards.

Therefore, phenoxyethanol is not added to ORALPEACE, which is an oral care product that can be taken orally and absorbed by the mucous membranes in infants and pregnant women.

Carryover ingredients that are not included in the ingredients of overseas products, such as preservatives as impurities contained in the product, which are not stated in the labeling of all ingredients, are prevented from being mixed in under the strict production control system in Japan.

Unlike overseas, it does not contain formaldehyde, which is strictly prohibited in Japan.

Many toothpaste products are white pastes because they contain many abrasives (compounds and stone powders) and foaming agents (soaps and surfactants).

However, in the case of a semi-transparent gel that does not turn white with a mild mixture of abrasives and foaming agents, if you add a component called “titanium oxide” as a coloring agent, the transparent one becomes a pure white paste.

“Titanium oxide” is made from minerals, but the World Health Organization points out that it is “carcinogenic”.

Since January 2020, France has banned the production and sale of food products containing “titanium oxide”.

ORALPEACE is a formulation that does not contain “titanium oxide” because it is made from only food ingredients that are safe to swallow.

No animal-derived ingredients are used.

We do not use any ingredients derived from animals, ingredients produced from the placenta of humans or domestic animals such as cows, pigs, sheep and horses, ingredients produced from animal eggs, and ingredients produced by culturing animal cells.

Also, we are not conducting animal experiments.

Regarding product manufacturing, we aim to create products that do not sacrifice the lives of animals.

We do not use ingredients such as cultivated bacteria ingested from dental plaque, excrement or plaque of humans or animals, or animal-derived bacteriocin, which is not approved as food.

First of all, as for plant extracts and essential oils, most of the raw materials in the world can be easily purchased at the essential oil shops on the Internet, so if you are expecting the effect of plant essential oils or herbal extracts on oral clinic, you can buy each raw material. We recommend that you try the effects of yourself.

ORALPEACE does not contain various plant essential oils or herbal extracts for antibacterial purposes.

The reason is as follows.

Plant essential oils and plant extracts have a sales promotion effect that makes consumers expect some effects when a large number of ingredients are added to products.

However, in reality, there was a problem that the expected clinical effects could not be obtained when added to oral care products.

For skin cosmetics, essential oils and plant extracts are predominantly used as fragrances, and vegetable oils are formulated as oils.

However, the problem is that oral care products that do not require fragrance or oil have almost no clinically expected effects.

It is necessary to increase the concentration in order to obtain some effect, but this will affect the taste and aroma, resulting in a taste that cannot be put into the mouth.

On the other hand, there was a problem that it would have a negative effect on safety if the amount of the formulation did not affect the taste.

Even though it is derived from plants, there are many ingredients that have evolved to avoid living organisms, such as hinokitiol and tea catechin, that have not been fully verified as safe substances for living organisms and the human body.

Since plant essential oils and plant/herb extracts have not been the foods that humans have always liked since ancient times, we do not use them in ORALPEACE.

If antibacterial properties are expected, the antibacterial activity of “Neonisin-e®” is several thousand times that of plant essential oils and plant extracts. In other words, the same effect can be obtained with a few thousandths.

ORALPEACE is blended with plum fruit extract for “Neonisin-e®”, Damask rose essential oil, and mint essential oil for refreshing feeling.

It contains the minimum amount of plant essential oils and extracts that are essential for expecting clinical effects.

If you like vegetable essential oils and herbal extracts, please procure them from herbs and essential oil shops and use them together with ORALPEACE.

Not compounded.

It is the same reason as hinokitiol, high-concentration catechin, mastic resin, and pine resin.

This is because there is a problem that side effects are greater than effects on humans and pets.

Since many plants do not become extinct by being eaten by insects and herbivores, they have developed and evolved toxicity and repellency against living organisms, and survived the severe survival race of this earth for millions of years.

Plants that are highly toxic cannot be eaten by humans, just as insects and herbivores cannot.

Plants such as vegetables and fruits that humans can eat are limited to a very small number of plants on earth, as there are very few plants that can be eaten in natural forests.

However, vegetables and fruits that are safe to eat as they are, as well as most of the plants in the garden or familiar to you, have the power to kill bacteria and organisms at home by boiling them to a high concentration.

In a simple example, fungi and viruses do not propagate in the essential oil of plant distillation.

In addition, it is possible to obtain data that a highly concentrated component of a plant extract that seems to be safe to eat will inactivate bacteria and viruses in experiments in petri dishes.

However, if a plant that seems safe as it is is made into a substance with a high concentration to kill bacteria and organisms, side effects on humans and pets that are organisms are large, and it is difficult to put it in the mouth. There was a big problem that it could not be tasted as an oral care product, the amount of the mixture that could be expected to be effective could not be put into the mouth, and the actual product was meaningless unlike the image.

From the above, there has been a worldwide demand for the development of natural preparations that exhibit bactericidal effects even at extremely low concentrations.

ORALPEACE is a product with excellent “biodegradability”.

Since it is made from only plant-derived food ingredients, if it is discharged to the environment after its function is completed, it will be quickly metabolized and reused in the natural ecosystem, and the characteristics of the environment and the risk of pollution are extremely low. ..

It is truly an environmentally friendly oral care product.

On the other hand, many petroleum-derived synthetic bactericides, antibiotics, concentrated plant antibacterial agents, etc. have the characteristic of being “hard to decompose”, and even if they decompose, the decomposed products show toxicity in the natural world. There is also something to do.

Since its toxic effect is strong and long-lasting, it is feared that it will adversely affect the natural ecosystem, especially the microbial ecosystem.

Recently, in developed countries and around the world, the problem that persistent plastic waste has a negative impact on marine ecosystems has become a hot topic, and containers with low risk of environmental pollution and switching to plastic with good biodegradability have become popular. There is a great worldwide interest in raw materials that excel in biodegradability in harmony with the environment, such as alternatives to.

It is easy to imagine that in the future, these environmentally-friendly directions will not reverse, and that in the future, new eco-friendly products that are kind to the earth, highly sustainable, and beneficial to humankind will replace the mainstream of the world. I can do it.

ORALPEACE are not made from petroleum, which is a limited fossil raw material, but can be made from lactobacilli that live in plant-derived okara and edible plants, which are highly sustainable and have a low environmental impact. There is also.

Against this background, we hope that many people will use Oral Peace to leave a beautiful earth for the next generation.

ORALPEACE is a component that can be swallowed as it is, has high biodegradability, and needs for medical and nursing care in order to avoid the risk of aspiration of the oral cavity moisturizing agent on the nasopharynx and tongue, which may cause aspiration in the lungs. In order to meet the requirements, we spent a lot of time carefully selecting the ingredients and developing highly water-soluble and biodegradable products.

Generally, it is possible to increase the viscosity of gel by adding synthetic polymers, polymer compounds, synthetic thickeners, etc.

However, in that case, there will be problems in the use of elderly people, infants and infants who are not good at gargling and vomiting, pregnant women who do not want to take chemically synthesized components, and discharge into the natural environment.

In addition, when foods with a thickening effect such as agar are added, the problem of easy spoilage emerges, and the problem that synthetic preservatives and alcohol (ethanol) must be added will arise.

The moisturizing and thickening components of the oral peas are made of plant-derived glycerin and xanthan gum, which are highly water-soluble and are kept hygienic and used in foods.

Formulating with only water and plant-derived ingredients, it is difficult to balance the water-solubility/biodegradability of the product and the viscosity that is easy to handle, and as a result of repeated trial and error, the viscosity of water and plant-derived ingredients is increased to a certain degree. We have succeeded in commercialization with a fine prescription balance and a unique manufacturing method.

However, glycerin has the property of taking in water from the atmosphere, so that natural soap containing a large amount of glycerin will dissolve in a humid bathroom.

If you do not close the cap properly after use, or leave it in a humid place for a long time, it may take in moisture from the atmosphere and become loose. Also, if there is a lot of water on the toothbrush or hand, it will be difficult to put it on because it leans down.

Therefore, in order to keep the viscosity so that it is easy to pick up, please consider how to use it, such as tightly closing the cap after use, not storing it in a highly humid place, taking a dry brush or picking it up with your hand. I would appreciate it.

No plastic tube is used.

ORALPEACE tube packages are available in aluminum tube type and laminated tube type.

Plastic tube/container type (made of plastic only, contents that popped out will return, air will enter the container where the contents have disappeared, there will be gaps, the amount of the contents that can be seen through the sun will be transparent) , “Very low cost”, “It can be opened with one hand”, but it has “low confidentiality and easy to rot and needs to be mixed with a large amount of synthetic preservatives”. There is a demerit that “the component of is easy to deteriorate.”

For the above reasons, we are not using it in oral pieces made of delicate ingredients such as food and organic ingredients.

The advantage of the aluminum tube type is that it “has high airtightness and light-shielding properties, and the contents that have been put out once will not return.” On the other hand, it has the disadvantages of being “unusable”, such as “cannot be opened with one hand”, “sometimes overloaded”, and “tube breaks”.

Since the debut of the ORALPEACE in 2013, we have been using it since aluminum tubes are highly sensitive and are ideal for oralpieces that do not use synthetic preservatives.

However, in daily use at medical and nursing care sites and at home, we received many comments regarding the inconvenience (cannot be opened with one hand, aluminum will be cut, contents will not be exhausted to the end, etc.). ..

On the other hand, the laminated tube type, which we started to use in 2017, adopts the latest technology “Aluminum Barrier Lamination (ABL)” and is a material with layers of “PB, PET, aluminum, PB” stacked from the outside. ..

By sandwiching the aluminum layer in the laminate, it is possible to ensure the same level of airtightness and light shielding as an aluminum tube, and it has the property of protecting the contents without volatilizing the contents compared to a plastic tube.

It is more convenient to meet the demand for ease of use at medical/nursing sites and at home while maintaining the functionality of the aluminum tube without deterioration even after being left for 6 months in a aging test (temperature 40 degrees, humidity 75% etc.) The characteristics of conventional aluminum tubes are fully ensured as it was developed with consideration given to its characteristics.

Although the cost of the container is high, it is a tube that combines the functionality of aluminum tubes with the ease of use of plastic tubes.

At ORALPEACE , we would like to reflect the opinions of many patients and consumers and not only to research and develop the ingredients, but also to utilize the latest technology for packaging.

You can check the quality of the tube/container by taking into consideration the tube/container of the oral care product and checking the inside by opening the tube/container with scissors after use.

We recommend you to check by yourself.

Materials that can be said to be almost handmade, such as fermented lactic acid bacteria extract and expensive plant-derived raw materials, which are developed by investing a great deal of time and effort in basic research and technology development of new ingredients by research institutions The oral piece used is a very time-consuming and costly product.

In fact, unlike oral toothpaste, which is made by mixing cheap stone powder and synthetic surfactant in a tube and filling it in a tube, basic research produces original ingredients, blends expensive organic ingredients, and agitates/fills. Production control, packaging and box materials, patent control, pharmaceutical control, support for facilities for people with disabilities, creative, public relations, distribution to high-quality department stores, etc. Oral care products that seem to be considered do not have to be cheap, and it takes the same effort and cost as lotions and beauty liquids of several thousand yen to 10,000 yen or more made in the same process at the same factory. ..

However, the concept of the oral piece is to offer the product at a reasonable price while pursuing the effect and safety of the product.

Good products include price. With the goal of setting a reasonable price for households that can be used on a daily basis, all of our factories and distribution partners are making various efforts and efforts to develop products from scratch in order to achieve products at that price.

Honestly pursuing the ideal price for daily oral care products and the appropriate price for the product content, and aiming for a more affordable price for those who love oral pieces through corporate efforts We are.
(For 80g of Clean & Moisture Gel, 15ml per 1ml.)

Now is the time when the world can share knowledge on the Internet. You can easily check the ingredients contained in toothpaste/oral care products, their prices, and the research background of the products.

Even if you choose to purchase oral care products, check the “all ingredients” displayed on the product package without taking into account the effect expression and the suggested price that the seller sings. We ask you to search the ingredients online, check the research background of the product, whether the product is valuable to the price, and what kind of corporate attitude you are conducting research and production in manufacturing. We recommend that you make a judgment and make a smart choice.

In the future, ORALPEACE will continue to sincerely strive to create better value-added and better products for those who feel value and empathy for this research, products, and businesses. Thank you for your cooperation.

The ORALPEACE planning and development member was the pioneer in 2005 developing the first organic brand with organic certification such as oral care, body care and hair care, and has developed many organic certified brands.

What are natural organic products made for overseas consumers who are highly conscious of family health and environmental issues?
Uses plant materials that can be produced sustainably without using fossil (petroleum) materials. Plants use endless organic cultivation and wild craft materials. Chemically synthesized ingredients and additives that have an impact on the human body and environment. I think that the aim is to create a product with the concept of not using etc.

ORALPEACE have also been developed by members who have been involved in the planning and development of various organic products and oral care products based on European organic standards for more than 15 years, and are still certified plants based on international organic product standards. It is produced in.

Regarding the organic product certification mark, until 2017, Oral Piece also acquired the European organic certification for each product and marked the product with the mark. However, the claims from the certification company (certification business group) are large, and the listing of the certification mark is not as effective as expected, and the payment to the certification company and the product without making the decision to convert the certification cost to the consumer price. We have decided to stop posting on the website and continue to only manufacture products that comply with the certification standards.

In other words, the oral pieces are of the same quality as the organic certified products in the world.

However, there is a reality that organic and natural products, herbs and herbal medicines have not been able to meet the needs of various diseases that are diversifying as therapeutic agents.

In order to meet the medical and health needs of the new era, “addition of products” that contains a large number of various plant extracts that are expected to have the same effect as before, and “subtraction that uses as few chemical synthetic ingredients as possible for health” Aiming for “multiplication” to a completely different dimension in “product manufacturing”, basic research that responds to modern clinical issues by fusing R&D with Japan’s advanced science and medical technology based on biotechnology of the new era, It can be said that they are challenging the development of patented technology and the production of products in a new era.

Specifically, it is necessary to create products that do not use petroleum-derived ingredients even if they are raw materials that can be used in food, and do not use chemically-synthesized ingredients or alcohol (ethanol) even if they are natural or plant-derived Naturally, in addition to the above, the lactic acid bacterium bacterium derived from plants, which is kind to animals and the global environment, was invented over 10 years with the aim of achieving both efficacy and safety through industry-academia collaboration with advanced research institutions. The major difference is that it is an oral care product for the global market that originates from Japan, which is a research and technology-based nation, and contains the syn drug “Neonisin-e”.

It is also a big difference that it is a social product that is trying to utilize the research and technology not only for commercial purposes but for the creation of jobs for people with disabilities in vulnerable places around the world.

ORALPEACE is a product and business that was created in consideration of an important family. I’m sure that everyone will be able to convey that feeling through the product.

We hope that many people will use ORALPEACE.

Thank you for your continued support of ORALPEACE Project.

In modern science,

1. “All human indigenous bacteria cannot be classified as good or bad”

2. “There is no technology that can classify the same creatures as good or evil and control/reduce only one or raise/increase only one”

There is a thing.

It is said that about 500 kinds of bacteria, including those that have not yet been named, live in our oral cavity up to 1 trillion.

In modern modern science, identification of bacteria that cause tooth decay and periodontal disease among the indigenous bacteria in the oral cavity is progressing, but 
 all bacteria in the oral cavity including those that have no name The fact is that the separation of good bacteria and bad bacteria has not actually been done.

In the oral cavity, even indigenous bacteria, which are considered to be good, may have a bad effect depending on the situation (also called opportunistic bacteria), and on the contrary, it is described as a bad one that causes tooth decay and periodontal disease. It has not been scientifically ruled out that indigenous bacteria can also perform good functions such as suppressing bacterial invasion from the outside.

 In other words, there are no evidences regarding the judgment of good or evil of indigenous bacteria・Because it has not been clarified.

Next, bacteria are classified as Gram-positive bacteria, Gram-negative bacteria, fungi, etc., and are not classified as good bacteria or bad bacteria.
The latest technology to sort the same organisms as good and bad There is no point.

Like humans, animals, insects, and living things, if you use “poisons”, “insecticides”, and “bactericides”, good and bad people, good animals and bad animals, beneficial insects and pests The indigenous bacteria that form, the bait bacteria and viruses, and the good bacteria and the bad bacteria “act on both at the same time and both.”

The opposite is the same, but since the recent boom in lactic acid bacteria has increased the focus on “bacteria” in the beauty industry, focusing on “beneficial bacteria” and “beautiful skin bacteria” that have a good effect on the human body, the “beneficial bacteria” Even if you want to grow or increase “Beautiful skin bacteria”, “all bacteria including bad bacteria” will increase at the same time.

The following are the current findings in the world’s most advanced lactic acid bacteria research, that is, research on probiotics and lactic acid bacteria antibacterial peptides (bacteriocins).

The antibacterial substances and antibacterial peptides (bacteriocins) produced by lactic acid bacteria vary depending on the type, but there are many antibacterial spectra (ranges) ranging from narrow to wide.

For example, “Nisin A”, which was discovered for the first time in the world and is most famous, has the broadest antibacterial spectrum among lactic acid bacteriocins and controls most Gram-positive bacteria.

On the other hand, bacteriocin, which has a narrow antibacterial spectrum, controls only certain Gram-positive bacteria (Gram-positive bacteria closely related to the production bacteria).

It can be said that this is “a certain bacterium or bacteriocin controls by selecting a specific bad bacterium”, but unfortunately it also works with closely related Gram-positive bacteria. I will.

Among the closely related bacteria of Gram-positive bacteria, Streptococcus mutans which is a bad bacterium that causes tooth decay and selects “only”, “single action” bacteria, substances, and bacteriocins are still found in the world. not.

It is impossible to get rid of only “bad bacteria” among all bacteria.

On the contrary, it is impossible to nourish “good bacteria”, “beautiful skin bacteria” and “only” to give them an advantage and increase “good bacteria”, “beautiful skin bacteria” and “only”.

Health and beauty/moisturizing effect in the oral cavity by growing and increasing “beneficial bacteria” and “beautiful skin bacteria” by paying attention to the existence and effects of “good bacteria” and “beautiful skin bacteria” in the oral cavity and skin I understand that you want to ask for, but unfortunately, you also increase “bad bacteria.”

As an example, if nutrients such as “oligosaccharides” that lactic acid bacteria prefer are given to “good bacteria” and “beautiful skin bacteria”, they will also be nutritious to “bad bacteria”, and at the same time as “good bacteria” and “beautiful skin bacteria” Will increase in the same way.

It is actually difficult to fix new bacteria such as “beneficial bacteria” and “skin-cleansing bacteria” to the human body, and it is not possible to nourish only the “beneficial bacteria” and “skin-cleansing bacteria” that are indigenous to each person. In the end, it means that the bacterial flora composed of “beneficial bacteria”, “beautiful skin bacteria”, “bad bacteria”, etc. will not change, and if you give nutrition, “bad bacteria”, which has a relatively strong power, will also become healthy, We may also expand our power.

In other words, it is impossible for the human body to “control only by selecting bad bacteria” and “increasing only good bacteria and beautiful skin bacteria” with the latest science and technology.

The human beings on earth are the same as we humans, but they support each other, complement each other, act and live together, and coexist in balance.

All of them do not exist insignificantly, and in the situation where their respective functions and interactions are not elucidated in science, it is impossible to distinguish everything from good and evil, and it is not possible to distinguish superiority and inferiority. is.

Even in the same human being, it has been reported that the composition of salivary bacteria varies depending on ethnicity, family, and each person depending on heredity and living environment. For each person, more than several hundred types of oral bacteria are good or bad. It cannot be said that it can be separated into fungi.

The bacteria and flora that we have in the oral cavity, skin, and intestines are not those that we have from birth, but the bacteria and flora that are inherited from parents such as cheek rubbing and saliva contact from an early childhood. It can be said that genetically optimal bacteria protect the body.

Like human beings, living things have good and bad sides for a specific person or society, but they are born and exist because they are necessary, and live and coexist with their individual characteristics.

Invisible to our eyes, it is the same organism, bacteria.

The oral cavity suffers from trouble because it is one of the Gram-positive bacteria, Cariestobacilli, that lives in the mouth as an indigenous bacterium and does not usually cause any problems (it does something useful). Produce acid from food waste and sugar as food to cause dental caries, periodontal disease bacteria that are one of the Gram-negative bacteria “excessively increase” between the teeth to form biofilms, and cause inflammation of the gums. The cause is that it becomes dirty and the total number of bacteria “excessively increases” and flows into the lungs.

Oral care with oral pieces helps to keep the oral health and peace of mind by approaching trouble-causing bacteria that are present as oral bacteria and cause “too many” problems.

For details, please see the collection of papers.

As the price of various products increased, the “reasonability” (image of acceptable price) felt by consumers of “toothpaste” was very low.

The reason is that the prices of calcium carbonate and baking soda in the ingredients are low, consumers know it, and the past “toothpaste” producers were very honest, serious about consumers.

In addition, due to deflation that lasted for many years (economic uncertainties associated with falling prices), many producers around the world have taken on new research and research compared to producers in other growth fields such as ICT and biotechnology. It is also possible that this is the result of choosing a strategy of low profit and high sales, which is mass production/mass sale of low value-added and low-priced products, rather than creation of high value-added products through technological innovation.

Many consumers in this economy, especially before the epidemic of the new coronavirus, are more likely to buy a consumer good without technological innovation than investing in family health and reducing total spending due to high added value. Purchasing is a priority because we want to reduce spending, and there was a situation in which low-priced consumer goods were favored.

However, recently, even for manufacturing companies, the number of customers and the number of sales points will not increase as the population and product usage amount/scene will increase, and market share of counterfeit products of other companies will be put on the market due to low cost for research and development, and share due to low price advantage In the erosion battle of increasing sales by depriving customers, the physical strength such as sales maintenance and employee salaries is reaching the limit, and the price range is increased by repricing products to higher prices and strengthening branding to improve the customer unit price. Is progressing.

ORALPEACE is an oral hygiene agent that aims to create new markets by creating unprecedented high added value through technological innovation invented by research at university institutions in order to meet new world needs. Will be.

ORALPEACE is one of the world’s largest oral care products markets, born in 2013 in Japan, which has the highest elderly ratio in the world. “The elderly, pregnant women, vulnerable people such as infants, those who care about the health and natural environment of their families. It is a super niche market product specialized for.

The market is small in the world, and many companies are left behind niche markets where they do not start investing in new R&D or entering the market.

This is because the lifetime value (LTV/customer lifetime value) is low, the economic efficiency is low, and the business feasibility is low, that is, the company does not profit.

In Japan alone, more than 1.3 million people, mainly elderly people, die each year due to old age or illness.

This means that the number of domestic users who need oral peace will continue to decline by more than 1.3 million people each year.

However, even though the market is small, there are people left behind in the world who are in trouble, such as the elderly, fighters, infants and people who are not good at chemical ingredients.

Oral care products are the oral care products for people left behind in the world.

It is a product that was newly researched and developed by a research institute of a national university, giving priority to the health and happiness of many families without giving priority to corporate profits and economic efficiency.

In other words, in terms of business, the main business of Oral Peace itself is not an economic/profit activity, but a social contribution activity/CSR (Corporate Social Responsibility) that is somehow economically balanced. It is a CSV (Creating Shared Value) model that is completely independent and rare in the world.

As a business, it is a social business in which it is difficult to pursue economic efficiency, but due to a serious research background, there is no other oral hygiene agent in the world that specializes in oral care for people including the elderly and the weak. Has no social benefit.

It is a new value for human beings: “While you can instantly approach the bacteria that cause problems in the oral cavity at ultra-low concentration, you can also moisturize and feel safe when swallowed, with high biodegradability and low environmental impact.”

Although it is small now, we have not been able to convey this new invention and value to people all over the world, but 100 years from now, not only for the elderly and the vulnerable, but definitely for the people of the world to shift their orientation in this direction. You can imagine it going.

In this way, the application of lactic acid bacterium antibacterial peptide (bacteriocin) to the field of hygiene has created new value for humankind. Serious researchers from research institutes such as Kyushu University in Japan research daily with a bet on their lives. It is a result of hard work.

And it will be the world’s technological innovation created by a Japanese research institute that created a new market and provided new benefits to humanity that never existed before.

I think the technological innovation created by this Japanese research institute feels small now, but it can be said that it is a technology in maid-in-Japan that is getting more attention in the world over time.

Therefore, it takes a lot of time and money for basic research and development to provide essential value.

In fact, unlike oral toothpaste, which is made by mixing cheap stone powder and synthetic surfactant in a tube and filling it in a tube, basic research produces original ingredients, blends expensive organic ingredients, and agitates/fills. Production control, packaging and box materials, patent control, pharmaceutical control, support for facilities for people with disabilities, creative, public relations, distribution to high-quality department stores, etc. Oral care products that seem to be considered do not have to be cheap, and it takes the same effort and cost as lotions and beauty liquids of several thousand yen to 10,000 yen or more made in the same process at the same factory. ..

(Thus, because the production price of the product itself is high, low-price competition, advertising drops, retail store profits of 60% or more of the over-the-counter sales price, and if all items are not sold back to the manufacturer Is a difficult product.)

In addition, the product market and production volume are limited, and it is very laborious and costly to produce each piece because it is manufactured by the Japanese people by hand.

And in many cosmetics and consumer goods, materials such as boxes and containers have higher distribution costs such as profits from retail stores, and the reality is that the research and technology behind them are not evaluated economically.

However, since the recent coronavirus damage, the importance of oral hygiene as preventive care and health maintenance, mucosal absorption of chemical substances contained in oral care products, and the impact on the microbial ecosystem when discharged into the environment, Many people have noticed that consumer awareness of oral care products is changing rapidly.

ORALPEACE For Pet gel costs 1,200 yen for about 2 months.

That means 600 yen per month and 25 yen per day.

6000 yen

For many,

Bank transfer fees and overtime fees, monthly charges for mobile phones, WIFI and internet services, small lunches and meals, wine and alcohol, electricity and gas, daily meals, snacks, high speeds and gasoline, Parking fee, train fee, coffee and cigarette fee, electricity fee, WIFI fee, mobile phone fee, etc.


Those who are concerned about aspiration/drinking, who are not good at gargling and vomiting, who are in need of nursing care or who are fighting illness,
Those who are careful about the health of their families and who demand safety in what they eat and drink daily, those who keep in mind their daily health and preventive care, infants and pregnant women, and beautiful nature in the event of precious water disasters. Those who want to use oral care products in


Other costs for maintaining health, prices of ingredients with low organic vegetables and additives, prices of healthy foods and supplements, costs for sports and gyms, medical expenses when you get sick, medication costs, cosmetics and shampoo fees, I am worried about various things everyday…

Compared to

Through joint research with Kyushu University Graduate School of Agriculture, Kagoshima University Graduate School of Medical and Dental Science, National Center for Longevity Medical Research, Department of Oral Diseases, etc.

Researched and developed over 10 years,

Made in Japan, which is made by hand from materials and raw materials by people who live in Japan and have a family,

You can enjoy the unprecedented value of “being instantly approaching the bacteria causing the trouble in the oral cavity, it can also moisturize and is safe to swallow, has high biodegradability and has a low environmental load”.

Entering the designed boxes and tubes, they are lined up in hospitals, dental clinics, and department stores nationwide, and purchasing makes a social contribution.

Above all, to use for the health and happiness of the important family, and to invest in your own health so as not to disturb your family until the last day,

1,200 yen (600 yen a month),

Don’t you think it’s reasonable? (Lol)

ORALPEACE is in pursuit of affordable prices for those who feel value in family health and happy days.

For other questions, please see the page below.

“Frequently Asked Questions”

If you have any questions that are not included in the “Frequently Asked Questions”, please feel free to contact us using the contact form.

We also welcome messages about projects, research and products.

We would appreciate it if you could feel free to contact us using the contact form.

We look forward to your continued support of the ORALPEACE Project.


Search for #oralpeace, #oralpeace tags on Instagram to see oralpieces around the world.

We would be happy if everyone could improve their life with oral peace by adding the tags #oralpeace and #oralpeace and be connected to PEACE all over the world.

Best regard!!