2020/04/03 (Friday)

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About preventive measures for babies and children

Everyone is worried about your baby or child going out.

I think many moms are having trouble with hand washing, alcohol disinfection, gargling and masking.

Sometimes I have to go through the crowd, and I eat a lot of things.

In such a case, using ORALPEACE spray on your baby’s or children’s mouth and throat may be one of the preventive measures.

It is not possible to inactivate the new coronavirus, but if you clean your mouth and reduce the enzyme that spreads the virus, you can reduce the virus infection rate such as influenza by 1/10 There are research presentations.

ORALPEACE is researched and developed by Kyushu University in Japan, and it is safe to swallow, yet contains “Neonisin-e *” that suppresses the action of bad bacteria in your mouth, 100% edible ingredients, organic oral care. ..

It is an oral hygiene agent used in ICU of Japan National Center for Child Health and Development (formerly National Children’s Hospital).

Since synthetic bactericides, preservatives and other chemically synthesized components, alcohol (ethanol), honey and propolis are not used, they can be used by newborns. Delicious fruity mandarin orange flavor.

While keeping basic precautions such as boosting immunity, staying out of the crowd, putting on a mask, and cleaning your hands, you should also keep your mouth clean.

Until the vaccine is developed, I would like to protect my small life with various preventive measures against new coronavirus (COVID-19).

Researchers, clinicians and other ORALPEACE project members are working on research and information dissemination every day with the help of their own research and technology to contribute to protecting the health of everyone and their irreplaceable families.


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2020/03/25 (Wednesday)

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Let’s protect the family from the new coronavirus (COVID-19)

Now that no vaccine has been developed, people with illness, elderly people, infants, and other people who are at high risk of being infected should use various methods to prevent the disease and protect the lives of important family members.

Thoroughly take preventive measures such as thoroughly washing hands, gargle, boosting immunity, getting enough nutrition and sleep, staying away from crowded areas, do not touch your face with your hands, put on a mask, etc. We also need to bring together wisdom from all over the world to overcome this human crisis.

By the way, the other day, I also announced my opinion on toothpaste / oral care and viruses, and I would like to inform you about the possibility of “virus measures by oral care”.

A virus cannot live by itself, but propagates through bacteria. It then enters the respiratory tract and body through all entrances to the body, the mouth and nose.

However, it seems that little is known that oral health is associated with more severe viral infections.

Miscellaneous bacteria in the mouth excrete enzymes such as protease and neuraminidase as their metabolites. Proteases destroy proteins, and in a dirty state, viruses are more likely to enter through weak areas of the mucous membrane.

In a survey by the Dental Association, it was reported that thorough brushing of teeth and oral care and cleansing of the oral cavity drastically reduced the influenza incidence to 1/10.

Unlike the influenza virus, the new coronavirus (COVID-19) is unknown to humankind and a countermeasure has not been established, but it is considered to be a preventive measure.

It is important to keep your mouth clean by brushing your teeth and taking oral care. It has been suggested that oral care and tooth brushing with the lactic acid bacterium antibacterial peptide preparation “Neonisin-e” can reduce bacteria in the oral cavity and clean it.

In addition, when going out, I would like to try to prevent infections when I go out, where people gather, trains and buses, and when I meet people who are coughing after talking to many people. But there are also times when you can’t gargle right away.

In such cases, the usefulness of the “ORALPEACE Spray” product has been suggested. Lactobacillus antibacterial peptide formulation “Neonisin-e” is made from naturally derived food ingredients, plants and water, so it is safe to spray and swallow.

From the above, I would like to be aware of the health of the “mouth”, which is the entrance to all of the body, and try to keep the oral cavity clean by brushing teeth and taking oral care more than usual.

Until vaccines are developed, it is important to gather information on preventive measures announced by researchers and research institutions around the world and take preventive measures as much as possible in order to protect the lives of important family members. It is considered.

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2020/03/10 (Tuesday)

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A View on Coronavirus and ORALPEACE / Oral Care

[Remarks on new coronavirus (COVID-19) and ORALPEACE / oral care]

This is a reprint from the ORALPEACE project supporter Dr. Tanaka regarding the relationship between oral care and viral infection prevention. We hope that our long-standing research team on lactic acid bacteria antimicrobial peptides and clinical research will be of little help to the health of many people in times of emergency.


Usually, the dentist, otolaryngologist, head and neck surgeon will often consult the oral cavity. I will give my opinion as one of the otolaryngologists of the ORALPEACE support member.

I think that what is recently attracting attention in the field of infectious diseases is “why can brushing and oral care prevent or reduce viral infection?”

Viruses, including influenza viruses, have a structure in which a gene called nucleic acid is encapsulated in a protein called capsid (Note: New Coronavirus (COVID-19) is also wrapped in another protein called envelope).

Bacteria in the intestinal tract, including the oral cavity, also have a protein-degrading enzyme called protease.

In an unsanitary oral environment, many bacteria are present in the oral cavity, and many proteinases come into contact with viral capsids and envelopes.

As a result, capsids and envelopes of some viruses, including the influenza virus, are degraded by proteolytic enzymes, causing them to pop, which makes it easier for the virus to enter the mucosal cells, mainly the oral mucosa.

This is the reason why it is difficult to establish influenza virus infection when the bacterial flora in the oral cavity is kept normal and the amount of bacteria is reduced.

It may be more likely to enter the digestive tract mucosa, but as an otolaryngologist, I do not have enough knowledge on this point.

However, many intestinal bacteria have proteinases, and keeping the intestinal bacteria normal seems to be recommended from the viewpoint of preventing viral infection.

The conclusion comes to the end and is tedious and apologetic, but ORALPEACE is mainly based on the lactobacillus antibacterial bacteriocin preparation derived from “Okara” which is an edible food called “Neonisin-e”, and its safety and antibacterial action. Is also revealed in data from the Faculty of Dentistry at Kagoshima University.

The reason why it is okay to swallow is that it is made from only the lactic acid bacterium bacteriocin preparation derived from the food “Okara” and water and plant (food) ingredients.

And even considering the above mechanism, the risk of viral infection (although new coronavirus (COVID-19) is unknown as described below) is reduced if oral bacteria are reduced by ORALPEACE and tooth brushing / oral care. May help.

Like this time, I think the chance of getting an unknown virus on a large-scale cruise ship such as the Diamond Princess carrying 3,700 people is the first time, at least in the modern world where there is a record.

It has not been medically verified that the new coronavirus (COVID-19) suppresses infection through the oral mucosa.

However, at least it is a risk that even if you consider it because it is a product that can be swallowed without exhaling even on a cruise ship that may lack drinking water, and that there is already some medical evidence for suppressing oral bacteria (evidence). From the viewpoint of benefit ratio, I think that prevention of infection by ORALPEACE and oral hygiene is significant.


* The new coronavirus (COVID-19) is unknown, and it is thought that there are differences from the existing viruses. However, we would be grateful if people with illnesses, the elderly, infants and young children who seem to be at high risk can take possible preventive measures and save their lives. This comment is published not as a medical practice but as a view that contributes to the health of the people in an emergency.

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2020/03/03 (Tuesday)

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Introducing ORALPEACE online in the beauty magazine “MAQUIA”

[Introducing ORALPEACE online in the beauty magazine “MAQUIA” !!]

“Is oral care properly done? I will teach you how to make clean teeth and breath.”


The editorial department also pays attention! Items with higher-grade functions


A toothpaste and oral care gel made from only water and plant materials, which was born from about 10 years of research on lactic acid bacteria peptides. Toothpaste, oral care and moisturize with one brush.


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ORALPEACE project sent free distribution of ORALPEACE products to 3,600 passengers and crews on the Yokohama Port cruise ship – “Diamond Princess”.

“Diamond Princess” has a collective infection of the new Corona Virus anchored in Yokohama Port.

According to prefectural Dental Association, there is a research reports that you will be able to prevent the infection of the virus by purifying the oral cavity. We hope that ORALPEACE product will help to prevent infection and improve the quality of life of the people on board.

We are a small social venture, but we would like to do a little as our corporate social responsibility to help our customers from Japan and the world who are in trouble at “Diamond Princess”.

We hope everyone is safe from the viruses and hope everyone can go back to their home where lovely family lives.

On February 12, the ORALPEACE project (Yokohama City) will carry passengers and passengers on the large-scale passenger ship “Diamond Princess” that has been infected by the new coronavirus, which is moored at Yokohama Port via Yokohama City. For oral hygiene product “ORAL PEACE”, we provided free distribution support for about 3,600 people.

According to the prefectural dentist’s association, there is a research report that virus infection can be prevented 10 times by cleaning the oral cavity. We hope Yokohama’s oral hygiene products will be useful in preventing infection and improving quality of life for people who are having trouble on board.

Our company is a small social venture, but we are limited in what we can do, but we hope that it will be useful for customers from Japan and the world who are in trouble at this local office, Yokohama Port on the office side. , Through the Yokohama Municipal Economic Affairs Bureau, which has been nurtured by the generous support of the project since its inception, we supported it with a little effort.

And thanks to the staff of the Yokohama City Economic Bureau, we were able to deliver it. We would also like to thank the Nihon Keizai Shimbun for their kind support in this project.

It will be wonderful if we approach the concept of the ORALPEACE project, “a society in which each and every one of us supports each other in times of trouble.” We pray that everyone on board will be able to return to their loved ones as soon as possible.

[Reference Material]

“Relationship between oral care and viral infections”

The bacteria in the mouth excrete, as their metabolites, proteases and enzymes called neuraminidase, which destroy proteins. These enzymes have the property of making it easy for the influenza virus to enter cells through the mucous membrane of the respiratory tract. If the oral cavity is left unclean, the amount of protease and neuraminidase will increase, which will easily lead to the onset and aggravation of virus and influenza. A research conducted by a university institution found that cleaning oral cavity with oral care reduced the infection rate of influenza virus by a factor of 10, indicating that there is a correlation between viral infection and keeping oral cavity clean. It recognized.

What is “ORAL PEACE”?

An oral hygiene product containing a patented formulation “Neonisin-e®︎” that is safe to swallow while sterilizing bacteria that cause problems in the oral cavity. It is a safe ingredient that can be absorbed by the body, and is made from only natural ingredients based on lactic acid bacterium biotechnology research with the Kyushu University Agricultural Research Institute in Japan, etc. Another feature of the project is that people with disabilities all over the country engage in business and work to generate jobs and income. Since it can be used without water, support has been provided to the Hiroshima disaster area in 2014, the Kumamoto earthquake disaster area in 2016, the national heavy rain disaster area in 2018, and the typhoon disaster area in Chiba prefecture in 2019. The goods have been provided free of charge. Received “Yokohama Business Grand Prix 2014 Grand Prize”, “Japan Venture Award 2015 Grand Prize”, “Nippon Foundation Social Innovator 2016”, “2018 Japan Agricultural Chemistry Technology Award”, etc., the world’s largest academic publication in 2019 It was also featured in Springer’s book Entrepreneurship in the Asia-Pacific: Case Studies. Currently, it is provided from Yokohama Port to 10 countries as an oral hygiene agent from Yokohama, Japan.

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2020/02/15 (Saturday)

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~ Adults want to stick to it. Organic oral care
Please see the featured articles from here !

Baby is also safe. Toothpaste gel made from only plant ingredients that is OK to swallow
Care for babies who can not gargle well, outdoors when water is not enough, etc.
I wish I had toothpaste that I didn’t mind swallowing …

This “ORALPEACE CLEAN & MOISTURE” is something that people like to use.
It is made from only water and plant materials, and no chemically synthesized ingredients or alcohol are added.
It’s a toothpaste gel that’s as safe as food.

The content is a transparent gel, with plenty of foam, and it is refreshed.
It tastes like a light, light jelly and is popular with kids.


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2020/02/15 (Saturday)

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ORAL PEACE was introduced at the 29th “INTERSTYLE 2020” exhibition

[ORALPEACE was introduced at the 29th “INTERSTYLE 2020” exhibition]

We exhibited and introduced “INTERSTYLE 2020” ORALPEACE held in Yokohama !!

“INTERSTYLE 2020” is the 29th exhibition this year, focusing on board culture such as surfing and snowboarding, and outdoor and bicycles.
Surfing and skateboarding have become official events for world-class sporting events, and the fields that attract attention.

May ORALPEACE reach many board cultures and outdoor people.

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2020/01/27 (Monday)

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ORALPEACE, oral care for dogs launched in February

ORALPEACE, oral care for dogs launched in February

Trife (Yokohama City), which develops and sells oral care products, will improve the oral care product “ORALPEACE for Pet” for dogs and start sales in February. A new formulation “Neonisin-e” is newly added to prevent oral candida, which is an infectious disease, and is effective against almost all bacteria causing oral problems.

It is gel-like and is applied to the oral cavity using a special toothbrush or finger cot. Since it is made of only edible ingredients, it does not require rinsing of the mouth and there is no harm even if swallowed.

It was commercialized in response to voices from pet dogs and others who said, “I would like to provide periodontal care before tartar builds up,” and “I am worried about bad breath.”

Sold at veterinary hospitals, pet stores, department stores, online shops, etc.


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ORALPEACE for Pet Renewal Product will be on sale from February 4

[ORALPEACE for Pet Renewal Product will be on sale from February 4 !!]

Thank you for always using ORALPEACE for Pet.

This time, the product has been renewed, & an improved new product will be released in February 2020.

The new “ORALPEACE For Pet” has been upgraded to an unprecedented oral care product for pets by incorporating a new formulation “Neonisin-e®”, which covers almost all causative bacteria in the oral cavity. We also increase the volume, change the tube specifications, & improve the viscosity.

The homepage has been renewed accordingly, so we hope you’ll see it when you have time.



Corresponds to oral Candida with damask rose formulation

An unprecedented oral care product for pets containing “Neonisin-e” that covers almost all oral causative bacteria

The renewed “ORALPEACE For Pet” will be released simultaneously in Japan and overseas markets

-Increased effect, increased amount, package change, improved viscosity, more delicious & easier to use product-

● Point of renewal

Changed from Neonisin, which was weak to oral cans, to a new formulation, Neonisin-e, which was upgraded with the use of Bulgarian damask rose essential oil. It has become an unprecedented oral care product for pets covering all oral causal bacteria.

Improves usability by adopting aluminum laminated laminate tube & flip top cap.

Shell capacity increased to 80 crumbs. Due to the effects, feeling of use, specifications & changes in capacity, the price is reduced to ¥ 1,200 (excluding tax). We couldn’t avoid price increase due to increased cost, but we maintained easy-to-use price for quality.

Improves the viscosity of the shell, while keeping the edible ingredients of natural origin at 100%, the shell is easy to pick up & has a good texture. For a more natural & gentle taste.

The case design is a sophisticated design. (Won GoodDesign Award 2017)

● Product information
“Neonisin-e *” combination, oral care health gel for dogs
Oral care that can be used forever for irreplaceable family health. With a special toothbrush, finger cot & clean gauze, just apply it in the mouth. Of course, you don’t need to rinse your mouth. If you do not want to open your mouth, it is effective to dissolve in drinking water. Completely free of chemically synthesized components. No synthetic preservatives or synthetic germicides are used. All ingredients except water are made from plants, giving a gentle & refreshing taste. It is a soft, colorless & transparent gel.

Contents: 80g Price: 1,200 yen (excluding tax)

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ORALPEACE’s special TV program was broadcast nationwide! Change the World-Aspirations for Building the Future-“Toothpaste without Water in Stricken Areas”

[ORALPEACE’s special TV program was broadcast nationwide! Change the World-Aspirations for Building the Future-“Toothpaste without Water in Stricken Areas”]

TV TOKYO information, documentary program
Change the World-Building the Future-“Toothpaste without Water”

This summer, there is a miracle toothpaste in Chiba Prefecture, which was hit by a typhoon, which helped live in the affected areas. You can brush your teeth without using water & swallow it! What is the secret?

Program contents
This summer, a toothpaste that can brush without water has been very active in Chiba Prefecture, which was hit by a typhoon & suffered from power outages & water cuts. Developed by Daisuke Teshima of ORALPEACE. Made from natural ingredients such as tofu and plum, it is safe to swallow. The trigger of the development was the appearance of my father, who was living a fighting illness in late cancer. He was too weak & swallowed even after brushing his teeth. Currently, it is helping people in 20 countries around the world, not just in the affected areas.


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