2020/08/06 (Thursday)-News

(JP) 「ISETAN HOME HOTEL」にて「オーラルピース」がご紹介

Sorry, this entry is only available in Japanese.

2020/08/05 (Wednesday)-お知らせ

(JP) 「ポビドンヨード」と「ネオナイシン-e」の違いについて

Sorry, this entry is only available in Japanese.

2020/07/22 (Wednesday)-新製品情報

待望のホワイトニング機能が追加 歯質別にケア®︎できる「オーラルピース クリーン&ホワイト」日本・海外市場で同時発売へ

Sorry, this entry is only available in Japanese.

2020/07/03 (Friday)-News

Regarding the container of ORAL PEACE

【Regarding the container of ORALPEACE】

ORALPEACE tubes are available in aluminum tube type and laminated tube type.

The plastic tube/container type (made of plastic, the contents that come out are returned, and the amount of the contents that can be seen through the sun can be seen through) is said to be “very cheap” and “open with one hand” There are merits.

However, it has a demerit that “it is not confidential and it easily rots, and it is necessary to use a lot of synthetic preservatives.” Not used with ORALPEACE.

The advantage of the aluminum tube type is that it “has high airtightness and light-shielding properties, and the contents that have been left out once do not return.”

On the other hand, it has the disadvantages of being “unusable” such as “cannot be opened with one hand”, “sometimes overloaded”, and “tube breaks”.

Since the debut of ORALPEACE in 2013, aluminum tubes have been used so far because they are highly sensitive and are best suited for oral pieces that do not use synthetic preservatives.

However, in daily use at medical and nursing care sites and at home, we received many comments regarding inconvenience (cannot be opened with one hand, aluminum is cut, contents cannot be cut out to the end, etc.). ..

On the other hand, the laminated tube type that we started to use in ORALPEACE in 2017 adopted the latest technology, “Aluminum Barrier Lamination (ABL)”, and is a material with layers of “PB, PET, aluminum, PB” stacked from the outside.

By sandwiching the aluminum layer in the laminate, the airtightness and light-shielding properties equivalent to those of aluminum tubes can be ensured, and compared to plastic tubes, the contents do not volatilize and the contents can be protected.

It is more convenient to meet the demand for ease of use at medical/nursing sites and homes while maintaining the functionality of aluminum tubes without deterioration even after being left for 6 months in a aging test (temperature 40 degrees, humidity 75% etc.) The characteristics of conventional aluminum tubes are fully ensured as it was developed with consideration given to its characteristics.

Although the cost of the container is high, it is a tube that combines the advantages of the functionality of the aluminum tube and the ease of use of the plastic tube.

ORALPEACE reflects the voices of many patients and consumers, and we would like to not only research and develop the ingredients but also utilize the latest technology for packaging.

2020/06/24 (Wednesday)-メディア掲載

Articles on Oral Peace’s entry into the European market in “WWD Beauty”

【Articles on Oral Peace’s entry into the European market in “WWD Beauty”】

2020/06/15 (Monday)-メディア掲載

ORAL PEACE posted in “WWD Beauty”

[ORAL PEACE posted in “WWD Beauty”]

2020/06/11 (Thursday)-News

An article was published in the Japan Economic Newspaper about the launch of “ORALPEACE” in the European market

[An article was published in the Japan Economic Newspaper about the launch of “ORALPEACE” in the European market]

“ORALPEACE” finally obtained official export sales authorization in the European market and started market expansion
-Official export to EU and local sales approval obtained, launched in September 2020-

ORALPEACE project has received official export and local sales approval to the EU and will start official sales in the European market from September 2020.

The EU has various strict regulations regarding the import and local sale of cosmetics, including the regulation of ingredients and the establishment of local managers.

Furthermore, regarding the submission of product information to the EU Commission, the “Cosmetics Regulations 1223/2009 (Cosmetics Regulations)” are stipulated in detail.

Exporting oral care products from Japan has been a significant barrier to entry for small Japanese social venture companies.

This time, I met a great European entrepreneur and partner, and received a lot of support, and I realized the effort.

Similar to the markets in the United States, Mexico, China, Hong Kong, Taiwan, Malaysia, Singapore and Australia, where we are already developing business, we manufacture products at laboratories and factories in Japan and export from Yokohama Port.

In Europe, there is a strong consumer awareness of what can be put in the mouth, and there is also a great deal of interest in environmental impact. In addition, the emergence of the coronavirus has raised awareness of oral hygiene in people. Therefore, the local release of “ORAL PEACE” was highly anticipated.

Therefore, local sales in Europe of “ORAL PEACE” with the following characteristics, which was realized by biotechnology research of Japanese industry-academia-government collaboration that has never existed before, can be a great consumer benefit.

“Immediately sterilizing the causative bacteria in the oral cavity with ultra-low concentration, it is made of only food and organic ingredients and safe to swallow, and even if it is vomited into the environment, it is quickly biodegraded and does not burden the microbial ecosystem.”

We will continue to make efforts to deliver ORAL PEACE to the world as soon as possible for many people who are in trouble.

ORALPEACE Product Overview:

An oral hygiene product containing the world-leading patented formulation “Neonisin-e”, which has an excellent bactericidal effect against bacteria causing troubles in the oral cavity but is safe to swallow and has a low environmental load.

Made from 100% natural ingredients based on the world’s most advanced lactic acid bacterium biotechnology research with Kyushu University and the National Center for Longevity Medical Research, etc., for the needs of oral care that is safe even if absorbed by the body.

Another characteristic of this project is the Social Contribution (CSV) project, which is run by a project supporter consisting of 2 employees and more than 100 professionals in each industry, and creates jobs and income for people with disabilities throughout the country.

Won “Yokohama Business Grand Prix 2014 Grand Prize”, “Japan Venture Award 2015 Grand Prize”, “Nippon Foundation Social Innovator 2016”, “2018 Japan Agricultural Chemistry Technology Award”, etc., the world’s largest academic publication in 2019 It was also featured in Springer’s book Entrepreneurship in the Asia-Pacific: Case Studies.

Currently, it is offered to 10 countries as a global oral hygiene brand from Yokohama, Japan.

In February of this year, we also provided free of charge to 3,600 crew members of the “Diamond Princess”, a coronavirus outbreak cruise ship anchored at Yokohama Port.

2020/03/10 (Tuesday)-お知らせ

A View on Coronavirus and ORALPEACE / Oral Care

[Remarks on new coronavirus (COVID-19) and ORALPEACE / oral care]

This is a reprint from the ORALPEACE project supporter Dr. Tanaka regarding the relationship between oral care and viral infection prevention. We hope that our long-standing research team on lactic acid bacteria antimicrobial peptides and clinical research will be of little help to the health of many people in times of emergency.


Usually, the dentist, otolaryngologist, head and neck surgeon will often consult the oral cavity. I will give my opinion as one of the otolaryngologists of the ORALPEACE support member.

I think that what is recently attracting attention in the field of infectious diseases is “why can brushing and oral care prevent or reduce viral infection?”

Viruses, including influenza viruses, have a structure in which a gene called nucleic acid is encapsulated in a protein called capsid (Note: New Coronavirus (COVID-19) is also wrapped in another protein called envelope).

Bacteria in the intestinal tract, including the oral cavity, also have a protein-degrading enzyme called protease.

In an unsanitary oral environment, many bacteria are present in the oral cavity, and many proteinases come into contact with viral capsids and envelopes.

As a result, capsids and envelopes of some viruses, including the influenza virus, are degraded by proteolytic enzymes, causing them to pop, which makes it easier for the virus to enter the mucosal cells, mainly the oral mucosa.

This is the reason why it is difficult to establish influenza virus infection when the bacterial flora in the oral cavity is kept normal and the amount of bacteria is reduced.

It may be more likely to enter the digestive tract mucosa, but as an otolaryngologist, I do not have enough knowledge on this point.

However, many intestinal bacteria have proteinases, and keeping the intestinal bacteria normal seems to be recommended from the viewpoint of preventing viral infection.

The conclusion comes to the end and is tedious and apologetic, but ORALPEACE is mainly based on the lactobacillus antibacterial bacteriocin preparation derived from “Okara” which is an edible food called “Neonisin-e”, and its safety and antibacterial action. Is also revealed in data from the Faculty of Dentistry at Kagoshima University.

The reason why it is okay to swallow is that it is made from only the lactic acid bacterium bacteriocin preparation derived from the food “Okara” and water and plant (food) ingredients.

And even considering the above mechanism, the risk of viral infection (although new coronavirus (COVID-19) is unknown as described below) is reduced if oral bacteria are reduced by ORALPEACE and tooth brushing / oral care. May help.

Like this time, I think the chance of getting an unknown virus on a large-scale cruise ship such as the Diamond Princess carrying 3,700 people is the first time, at least in the modern world where there is a record.

It has not been medically verified that the new coronavirus (COVID-19) suppresses infection through the oral mucosa.

However, at least it is a risk that even if you consider it because it is a product that can be swallowed without exhaling even on a cruise ship that may lack drinking water, and that there is already some medical evidence for suppressing oral bacteria (evidence). From the viewpoint of benefit ratio, I think that prevention of infection by ORALPEACE and oral hygiene is significant.


* The new coronavirus (COVID-19) is unknown, and it is thought that there are differences from the existing viruses. However, we would be grateful if people with illnesses, the elderly, infants and young children who seem to be at high risk can take possible preventive measures and save their lives. This comment is published not as a medical practice but as a view that contributes to the health of the people in an emergency.

2020/02/18 (Tuesday)-メディア掲載

(JP) 横浜港クルーズ船への支援活動について日本歯科新聞に取り上げていただきました

Sorry, this entry is only available in Japanese.

2020/02/16 (Sunday)-メディア掲載



ORALPEACE project sent free distribution of ORALPEACE products to 3,600 passengers and crews on the Yokohama Port cruise ship – “Diamond Princess”.

“Diamond Princess” has a collective infection of the new Corona Virus anchored in Yokohama Port.

According to prefectural Dental Association, there is a research reports that you will be able to prevent the infection of the virus by purifying the oral cavity. We hope that ORALPEACE product will help to prevent infection and improve the quality of life of the people on board.

We are a small social venture, but we would like to do a little as our corporate social responsibility to help our customers from Japan and the world who are in trouble at “Diamond Princess”.

We hope everyone is safe from the viruses and hope everyone can go back to their home where lovely family lives.

On February 12, the ORALPEACE project (Yokohama City) will carry passengers and passengers on the large-scale passenger ship “Diamond Princess” that has been infected by the new coronavirus, which is moored at Yokohama Port via Yokohama City. For oral hygiene product “ORALPEACE”, we provided free distribution support for about 3,600 people.

According to the prefectural dentist’s association, there is a research report that virus infection can be prevented 10 times by cleaning the oral cavity. We hope Yokohama’s oral hygiene products will be useful in preventing infection and improving quality of life for people who are having trouble on board.

Our company is a small social venture, but we are limited in what we can do, but we hope that it will be useful for customers from Japan and the world who are in trouble at this local office, Yokohama Port on the office side. , Through the Yokohama Municipal Economic Affairs Bureau, which has been nurtured by the generous support of the project since its inception, we supported it with a little effort.

And thanks to the staff of the Yokohama City Economic Bureau, we were able to deliver it. We would also like to thank the Nihon Keizai Shimbun for their kind support in this project.

It will be wonderful if we approach the concept of the ORALPEACE project, “a society in which each and every one of us supports each other in times of trouble.” We pray that everyone on board will be able to return to their loved ones as soon as possible.

[Reference Material]

“Relationship between oral care and viral infections”

The bacteria in the mouth excrete, as their metabolites, proteases and enzymes called neuraminidase, which destroy proteins. These enzymes have the property of making it easy for the influenza virus to enter cells through the mucous membrane of the respiratory tract. If the oral cavity is left unclean, the amount of protease and neuraminidase will increase, which will easily lead to the onset and aggravation of virus and influenza. A research conducted by a university institution found that cleaning oral cavity with oral care reduced the infection rate of influenza virus by a factor of 10, indicating that there is a correlation between viral infection and keeping oral cavity clean. It recognized.

What is “ORALPEACE”?

An oral hygiene product containing a patented formulation “Neonisin-e®︎” that is safe to swallow while sterilizing bacteria that cause problems in the oral cavity. It is a safe ingredient that can be absorbed by the body, and is made from only natural ingredients based on lactic acid bacterium biotechnology research with the Kyushu University Agricultural Research Institute in Japan, etc. Another feature of the project is that people with disabilities all over the country engage in business and work to generate jobs and income. Since it can be used without water, support has been provided to the Hiroshima disaster area in 2014, the Kumamoto earthquake disaster area in 2016, the national heavy rain disaster area in 2018, and the typhoon disaster area in Chiba prefecture in 2019. The goods have been provided free of charge. Received “Yokohama Business Grand Prix 2014 Grand Prize”, “Japan Venture Award 2015 Grand Prize”, “Nippon Foundation Social Innovator 2016”, “2018 Japan Agricultural Chemistry Technology Award”, etc., the world’s largest academic publication in 2019 It was also featured in Springer’s book Entrepreneurship in the Asia-Pacific: Case Studies. Currently, it is provided from Yokohama Port to 10 countries as an oral hygiene agent from Yokohama, Japan.

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